Study on the anti-cerebral ischemia effect of borneol and its mechanism [PDF]
, 2013 Background: Borneol is the processed item from resin of Dryobalanops aromatica Gaertn. f. It can enhance the activity of antioxidant enzymes in brain tissue and reduce inflammatory response by improving the energy metabolism of ischemic brain regions ...
Chu, X +5 more
core +2 more sources
Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging
Advanced Science, EarlyView.The functional integration of benefits from small semiconducting dyes and biocompatible serum proteins ushered in a new frontier of deep wide‐field in vivo imaging technique, affording valuable pathophysiological insight into the functioning of neurovascular unit in space and time.
Si Chen +9 more
wiley +1 more source
TGIF1 overexpression promotes glioma progression and worsens patient prognosis
Cancer Medicine, Volume 11, Issue 24, Page 5113-5128, December 2022., 2022 This study is the first to comprehensively analyze and reveal TGIF1, as a new oncogene, is closely related to the malignancy‐related phenotype of glioma, and that TGIF1 could be an independent risk factor for poor prognosis of glioma, which is expected to become a new target for individualized treatment of glioma patients.
Baoya Wang +5 more
wiley +1 more source
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]
Brain Research 1007(1-2): 98-108 (2004), 2007 Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved in ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and neurological deficits in a standardized model of transient focal cerebral ischemia in rats.
arxiv
Integration of Clinical, Biological, and Computational Perspectives to Support Cerebral Autoregulatory Informed Clinical Decision Making Decomposing Cerebral Autoregulation using Mechanistic Timescales to Support Clinical Decision-Making [PDF]
arXiv, 2022 Adequate brain perfusion is required for proper brain function and life. Maintaining optimal brain perfusion to avoid secondary brain injury is one of the main concerns of neurocritical care. Cerebral autoregulation is responsible for maintaining optimal brain perfusion despite pressure derangements. Knowledge of cerebral autoregulatory function should
arxiv
Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds. [PDF]
, 2017 Previously, we only apply a traditional Chinese medicine (TCM) Danshen-Chuanxiong-Honghua (DCH) for cardioprotection via anti-inflammation in rats of acute myocardial infarction by occluding coronary artery. Presently, we select not only DCH but also its
Fushun Wang +9 more
core +3 more sources
Ligustrazine monomer against cerebral ischemia/reperfusion injury
Neural Regeneration Research, 2015 Ligustrazine (2,3,5,6-tetramethylpyrazine) is a major active ingredient of the Szechwan lovage rhizome and is extensively used in treatment of ischemic cerebrovascular disease.
Haijun Gao +9 more
semanticscholar +1 more source
Case of a 96‐year‐old woman with tilt of the subjective vertical axis
Annals of Clinical and Translational Neurology, EarlyView.
Markus A. Hobert +4 more
wiley +1 more source
Advanced Science, EarlyView.Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen +9 more
wiley +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022 Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan +4 more
wiley +1 more source