Results 121 to 130 of about 229,585 (170)
Some of the next articles are maybe not open access.
Hemichannels in Cerebral Ischemia
Current Molecular Medicine, 2009Hemichannels are transmembrane channels that represent the functional subunits of gap junctions. Each hemichannel is composed of a connexin or pannexin hexamer and, after being transported to the membrane, remains unpaired until it is incorporated in a gap junction. Several studies have already provided evidence that gap junction-mediated intercellular
Panagiotis, Bargiotas +2 more
openaire +2 more sources
Electrophysiology of cerebral ischemia
Neuropharmacology, 2008Organized brain activity requires the coordinated firing of vast numbers of nerve cells. To maintain this, all these cells must be adequately polarized, their axons capable of conducting action potentials and releasing transmitters at an even greater numbers of synapses. Hence the often dire consequences of any interruption in the normal supply of O(2)
openaire +2 more sources
Cerebral ischemia and inflammation
Current Opinion in Neurology, 2001Cerebral ischemia is accompanied by a marked inflammatory reaction that is initiated by ischemia-induced expression of cytokines, adhesion molecules, and other inflammatory mediators, including prostanoids and nitric oxide. Preclinical studies suggest that interventions that are aimed at attenuating such inflammation reduce the progression of brain ...
C, Iadecola, M, Alexander
openaire +2 more sources
Focal Cerebral Ischemia and Migraine
Cephalalgia, 1985Consistent literature data on the cerebrovascular risk in migraineous patients are lacking. Available preliminary clinical data (Italian Cooperative Cross-Sectional Case-Control Study) suggest that migraine can hardly be considered a relevant pathogenetic associated risk factor of focal cerebral ischemia.
PRENCIPE M +3 more
openaire +3 more sources
2011
Rodent models of focal cerebral ischemia have been extremely useful in elucidating pathomechanisms of human stroke. Most commonly, a monofilament is advanced through the internal carotid artery of rodents to occlude the origin of the middle cerebral artery thus leading to critical ischemia in the corresponding vascular territory.
Stefan, Braeuninger +3 more
openaire +2 more sources
Rodent models of focal cerebral ischemia have been extremely useful in elucidating pathomechanisms of human stroke. Most commonly, a monofilament is advanced through the internal carotid artery of rodents to occlude the origin of the middle cerebral artery thus leading to critical ischemia in the corresponding vascular territory.
Stefan, Braeuninger +3 more
openaire +2 more sources
Polyamines and cerebral ischemia
1998It has been well established that alterations in polyamine metabolism are associated with animal models of global ischemia. Recently, this has been extended to include models of focal ischemia and traumatic brain injury. There is much evidence to support the idea that polyamines may play a multifaceted detrimental role following ischemia reperfusion ...
openaire +2 more sources
Apoptosis and Cerebral Ischemia
Cerebrovascular Diseases, 2000W, Kuschinsky, F, Gillardon
openaire +2 more sources