Expensive cerebral blood flow measurements alone are useless and misinformative in comatose patients: a comprehensive alternative [PDF]
Arquivos de Neuro-Psiquiatria, 2003 Since the first report addressing quantification of cerebral blood flow (CBF), concomitant assessment of cerebral oxygen consumption was also carried out.
Julio Cruz
doaj +1 more source
Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia [PDF]
European Journal of Pharmacology 453(2-3): 189-195 (2002), 2007 Cyclooxygenase-2 is involved in the inflammatory component of the ischemic cascade, playing an important role in the delayed progression of the brain damage. The present study evaluated the pharmacological effects of the selective cyclooxygenase-2 inhibitor nimesulide on delayed neuronal death of hippocampal CA1 neurons following transient global ...
arxiv
Assessing the effect of statins in lowering the risk of stroke and preventing cerebral ischemia in patients with hypercholesterolemia [PDF]
, 2017 Numerous analyses have explored the role of statins in reducing stroke incidence, reducing cerebral ischemia in hypercholesterolemic patients, and preventing ischemic stroke.
AlSulaiman, Wafa
core
Protective effect of extract of Cordyceps sinensis in middle cerebral artery occlusion-induced focal cerebral ischemia in rats [PDF]
, 2010 Background Ischemic hypoxic brain injury often causes irreversible brain damage. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional medicines.
Guo, Jianyou +5 more
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MicroRNAs Regulate Mitochondrial Function in Cerebral Ischemia-Reperfusion Injury
International Journal of Molecular Sciences, 2015 Cerebral ischemia-reperfusion injury involves multiple independently fatal terminal pathways in the mitochondria. These pathways include the reactive oxygen species (ROS) generation caused by changes in mitochondrial membrane potential and calcium ...
Yue Hu +3 more
semanticscholar +1 more source
Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts
Advanced Science, EarlyView.Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin +9 more
wiley +1 more source
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]
Neuroscience Research 41(3): 233-241 (2001), 2007 The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min. After the end of ischemia and at different reperfusion times (2, 6, 12, 24, 48, 72, 96 h and 7 days), markers of lipid peroxidation, reduced and ...
arxiv
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]
, 2001 The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Al-Dalain, Saied M. +4 more
core
Advanced Science, EarlyView.The breakdown of the blood‐brain barrier (BBB) after cerebral ischemia can cause brain injury and induce potentially fatal consequences. Currently, there exist few dependable and low‐cost imaging techniques for visualizing the BBB. This investigation effectively engineered an albumin‐specific covalently tagged near‐infrared‐II (NIR‐II) dye, serving as ...
Jiajun Xu +6 more
wiley +1 more source
Effect of Saponin on Cerebral Edema Rate in An Animal Model of Stroke
Journal of Mazandaran University of Medical Sciences, 2022 Background and purpose: Oxidative stress and neuroinflammation are the main causes of cerebral ischemia. Saponin with steroid or triterpenoid compounds with a sugar part has strong antioxidant and anti-inflammatory properties.
Elmira Shiri +3 more
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