Results 131 to 140 of about 1,282,519 (402)

Toll-like receptors in cerebral ischemic inflammatory injury

open access: yesJournal of Neuroinflammation, 2011
Cerebral ischemia triggers acute inflammation, which has been associated with an increase in brain damage. The mechanisms that regulate the inflammatory response after cerebral ischemia are multifaceted.
Yang Qing-Wu, Lin Sen, Wang Yan-Chun
doaj   +1 more source

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

open access: yesAutophagy, 2014
Autophagy, a highly conserved process conferring cytoprotection against stress, contributes to the progression of cerebral ischemia. β-arrestins are multifunctional proteins that mediate receptor desensitization and serve as important signaling scaffolds
Pei Wang   +8 more
semanticscholar   +1 more source

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin   +10 more
wiley   +1 more source

Inhibition of central angiotensin-converting enzyme with enalapril protects the brain from ischemia/reperfusion injury in normotensive rat [PDF]

open access: yes
Background and the Purpose of the study: Central Angiotensin Converting Enzyme (ACE) has an important role on cerebral microcirculation and metabolism.
دهقان, غلامعباس   +1 more
core  

Corrigendum: Cerebral ischemia and neuroregeneration

open access: yesNeural Regeneration Research, 2022
[This corrects the article DOI: 10.4103/1673-5374.228711].
openaire   +3 more sources

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

open access: yesAdvanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber   +6 more
wiley   +1 more source

Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]

open access: yes, 1998
Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Bari, Ferenc   +2 more
core  

Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix

open access: yesAdvanced Science, EarlyView.
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang   +16 more
wiley   +1 more source

Estimation of thiocetam influence on glutathione link of thiol disulfide cerebral system in conditions of experimental chronic ischemia

open access: yesPatologìâ, 2015
Aim. Pharmacological remodeling of pathologic changes when cerebral ischemia takes place is actual task for today. With the purpose of thiocetam neuroprotective properties studying in conditions of experimental chronic cerebral ischemia the ...
A. V. Demchenko, І. F. Belenichev
doaj   +1 more source

Chrysin Protects against Focal Cerebral Ischemia/Reperfusion Injury in Mice through Attenuation of Oxidative Stress and Inflammation

open access: yesInternational Journal of Molecular Sciences, 2014
Inflammation and oxidative stress play an important part in the pathogenesis of focal cerebral ischemia/reperfusion (I/R) injury, resulting in neuronal death.
Yang Yao   +6 more
semanticscholar   +1 more source

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