Results 141 to 150 of about 161,579 (302)

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Transcriptomics, single-cell sequencing and spatial sequencing-based studies of cerebral ischemia

European Journal of Medical Research
With high disability and mortality rate as well as highly complex pathogenesis, cerebral ischemia is highly morbid, prone to recurrence. To comprehensively understand the pathophysiological process of cerebral ischemia and to find new therapeutic ...
Jiaming Liu, Tao Qing, Mei he, Liu Xu, Zhuxiang Wu, Meiting Huang, Zheyu Liu, Ye Zhang, Zisheng Li, Wenhui Yang, Junbo Liu, Jie Li   +11 more
doaj   +1 more source

Book Reviews : Cerebral Ischemia, Molecular and Cellular Patho physiology—Contemporary Neuroscience. Wolfgang Walz (ed.) with 16 contributors. Humana Press, Totowa, NJ, 1999, 278 pp., Illustrated, $125.00 [PDF]

, 1999
William H. Wehrmacher, Harry L. Messmore
openalex   +1 more source

Prognostic Utility of the Preoperative Cachexia Index in Patients Undergoing Emergency Laparotomy

Annals of Gastroenterological Surgery, EarlyView.
The preoperative cachexia index, incorporating muscle mass, nutritional status, and inflammation, predicts in‐hospital and one‐year mortality in patients undergoing emergency laparotomy. This simple index may aid in risk stratification and perioperative decision‐making in high‐risk surgical patients. ABSTRACT Aim Emergency laparotomy is associated with
Naoko Fukushima, Takahiro Masuda, Kazuto Tsuboi, Masami Yuda, Keita Takahashi, Fumiaki Yano, Ken Eto   +6 more
wiley   +1 more source

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

Annals of Gastroenterological Surgery, EarlyView.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori, Hiromitsu Maehira, Nobuhito Nitta, Takeru Maekawa, Toru Miyake, Sachiko Kaida, Masatsugu Kojima, Katsushi Takebayashi, Takeshi Sonoda, Masaji Tani   +9 more
wiley   +1 more source

Neuroprotective effects of human bone marrow mesenchymal stem cells against cerebral ischemia are mediated in part by an anti-apoptotic mechanism

, 2019
CesarV Borlongan, Yuyang Zhang, Seong‐Jin Yu, JulianP Tuazon, Jea-Young Lee, Sydney Corey, Lauren Kvederis, Chase Kingsbury, Yuji Kaneko   +8 more
openalex   +1 more source

Psoas Muscle Volume as a Predictor of Postoperative Complications in Patients Undergoing Emergency Surgery for Strangulated Small Bowel Obstruction: A Retrospective Single‐Center Study

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study identified low preoperative psoas muscle volume, measured by computed tomography, as an independent predictor of postoperative complications in patients undergoing emergency surgery for strangulated small bowel obstruction. Low psoas muscle volume, particularly in older adults, was associated with cardiopulmonary and systemic ...
Takuya Shiraishi, Chika Katayama, Yuta Shibasaki, Chika Komine, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Hiroomi Ogawa, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Neuroprotective effects of electroacupuncture in ischemic stroke: from mechanisms to clinical implications

Frontiers in Aging Neuroscience
Ischemic stroke is a condition caused by an interruption of blood flow to the brain that can lead to neurological damage. The severe neurological damage caused by an ischemic stroke can lead to cognitive impairment and even disability.
Jinxi Zhu, Jinxi Zhu, Jinxi Zhu, Xinyi Ge, Xinyi Ge, Xinyi Ge, Yulong Cao, Yulong Cao, Yulong Cao, Renjie Xiao, Xiao Deng   +10 more
doaj   +1 more source

Predictive value of cerebrovascular time constant for delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage [PDF]

Agnieszka Uryga, Magdalena Kasprowicz, Karol P. Budohoski, Nathalie Nasr, Marek Czosnyka   +4 more
openalex   +1 more source

Magnesium Sulfate Treatment after Transient Hypoxia-Ischemia in the Newborn Piglet Does Not Protect against Cerebral Damage [PDF]

, 2000
Kirsty Greenwood, P. Cox, Huseyin Mehmet, Juliet Penrice, Philip Amess, Ernest B. Cady, John Wyatt, A. David Edwards   +7 more
openalex   +1 more source