Results 271 to 280 of about 1,244,067 (429)

Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions. [PDF]

open access: yesAntioxidants (Basel)
Belenichev I   +7 more
europepmc   +1 more source

Kurarinone alleviates hemin‐induced neuroinflammation and microglia‐mediated neurotoxicity by shifting microglial M1/M2 polarization via regulating the IGF1/PI3K/Akt signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 38, Issue 12, Page 1213-1223, December 2022., 2022
Abstract Cerebral hemorrhage is a fatal disease that causes severe damage to local nerve function. The purpose of this research is to analyze the effect of kurarinone on hemin‐induced neuroinflammation and neurotoxicity. In our study, according to the results of bioinformatics analysis, we hypothesized that kurarinone might modulate cerebral hemorrhage
Zeng‐Qiang Jia   +2 more
wiley   +1 more source

Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia [PDF]

open access: hybrid, 1989
Eva Westerberg   +4 more
openalex   +1 more source

Protective effects of cedrol against transient global cerebral ischemia/reperfusion injury in rat. [PDF]

open access: yesBMC Complement Med Ther
Asgharzade S   +3 more
europepmc   +1 more source

HMGB1 blood levels and neurological outcomes after traumatic brain injury: Insights from an exploratory study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Posttraumatic epilepsy (PTE) and cognitive impairment are severe complications following traumatic brain injury (TBI). Neuroinflammation likely contributes, but the role of specific inflammatory mediators requires clarification. High‐mobility group box 1 (HMGB1) is an inflammatory cytokine released after brain injury that may be ...
Irma Wati Ngadimon   +12 more
wiley   +1 more source

CircUCK2 regulates HECTD1‐mediated endothelial‐mesenchymal transition inhibition by interacting with FUS and protects the blood–brain barrier in ischemic stroke

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 39, Issue 1, Page 40-51, January 2023., 2023
Abstract Ischemic stroke (IS) has become a cerebrovascular disease of widespread concern. Overexpression of circUCK2 alleviates neuronal damage in IS. However, the specific regulatory mechanisms of circUCK2 are not fully understood. In this study, we found that circUCK2 and HECT domain E3 ubiquitin ligase 1 (HECTD1) were downregulated in IS models in ...
Jun‐Hong Zhuang   +8 more
wiley   +1 more source

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