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Total Cerebral Ischemia in the Dog
Archives of Surgery, 1962In a previous report1we described a simple method of selectively cooling the brain as a possible method of allowing prolonged interruption of the cerebral circulation. It was apparent then that exact knowledge of the time tolerance of the brain to ischemia at various cerebral temperatures was needed if this technique was going to be applied clinically.
Robert J. Boyd, John E. Connolly
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Adenosine Receptors in Cerebral Ischemia
2014Ischemic stroke is a complex pathology characterized by a sequence of events that evolve over time and space. It is the second leading cause of death and the main cause of adult long-term disability in developed countries. At the moment, there is no promising pharmacotherapy for acute ischemic stroke.
MELANI, ALESSIA +2 more
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Excitotoxicity in Cerebral Ischemia
2004The hypothesis that cerebral ischemia may recognize an excitoxic pathophysiological component is supported by a number of consolidated arguments, including the neuroprotective activity of glutamate receptor antagonists in experimental animal models and the use of anti-excitotoxic agents in clinical trials for stroke. Despite the dramatic results in the
Flavio Moroni +2 more
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Apoptosis and Cerebral Ischemia
Cerebrovascular Diseases, 2000Wolfgang Kuschinsky, Frank Gillardon
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Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion
Signal Transduction and Targeted Therapy, 2022Yang Shu, Yu-Jie Guo, Scott Ayton
exaly
Ischemia and reperfusion—from mechanism to translation
Nature Medicine, 2011Holger K Eltzschig, Tobias Eckle
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