Results 31 to 40 of about 349,423 (310)

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

Neuroprotective effect of baicalin on focal cerebral ischemia in rats

open access: yesNeural Regeneration Research, 2018
Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease.
Jiong Dai   +8 more
doaj   +1 more source

Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia

open access: yesJournal of Diabetes Research, 2020
Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao   +5 more
doaj   +1 more source

Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]

open access: yes, 2002
Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh   +5 more
core   +1 more source

Exercise preconditioning exhibits neuroprotective effects on hippocampal CA1 neuronal damage after cerebral ischemia

open access: yesNeural Regeneration Research, 2015
Recent evidence has suggested the neuroprotective effects of physical exercise on cerebral ischemic injury. However, the role of physical exercise in cerebral ischemia-induced hippocampal damage remains controversial.
Nabi Shamsaei   +4 more
doaj   +1 more source

Variability of the Heart Rhythm as an Additional Marker for Determining Vegetative Functions in Patients with Chronic Cerebral Ischemia [PDF]

open access: yes, 2018
Aim. Practical cardiology is in constant search for non-invasive vascular risk markers. Heart rhythm reflects the body\u27s response to various stimuli of the external and internal environment. Heart rate variability (HRV) has a prognostic and diagnostic
Inhula, N. (Nataliia)
core   +2 more sources

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

open access: yesNeural Regeneration Research, 2015
The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia.
Ya-yun Yan   +7 more
doaj   +1 more source

CaMKII in cerebral ischemia [PDF]

open access: yesActa Pharmacologica Sinica, 2011
Ischemic insults on neurons trigger excessive, pathological glutamate release that causes Ca²⁺ overload resulting in neuronal cell death (excitotoxicity). The Ca²⁺/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a major mediator of physiological excitatory glutamate signals underlying neuronal plasticity and learning. Glutamate stimuli trigger
Steven J, Coultrap   +4 more
openaire   +2 more sources

12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation

open access: yesNeural Regeneration Research, 2015
Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini   +4 more
doaj   +1 more source

Early changes in transient adenosine during cerebral ischemia and reperfusion injury. [PDF]

open access: yesPLoS ONE, 2018
Adenosine is an important neuromodulator in the central nervous system, and tissue adenosine levels increase during ischemic events, attenuating excitotoxic neuronal injury.
Mallikarjunarao Ganesana, B Jill Venton
doaj   +1 more source

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