Results 11 to 20 of about 229,240 (269)
PLoS ONE, 2021 Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels, and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces secretion of pro-inflammatory cytokines.
Il-Gyu Ko +7 more
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MicroRNAs in Cerebral Ischemia [PDF]
Stroke Research and Treatment, 2013 The risk of ischemic stroke increases substantially with age, making it the third leading cause of death and the leading cause of long-term disability in the world. Numerous studies demonstrated that genes, RNAs, and proteins are involved in the occurrence and development of stroke. Current studies found that microRNAs (miRNAs or miRs) are also closely
Yang Wang, Yongting Wang, Guo-Yuan Yang
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AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway
Brain and Behavior, 2021 Background Cerebral ischemia/reperfusion injury is a severe problem in patients with brain ischemia. Brain injury caused by the immune response is important in the pathogenesis of cerebral ischemia/reperfusion injury and immune pathways.
Lichao Fan, Lichun Zhou
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Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages
Frontiers in Cellular Neuroscience, 2017 In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains a ...
Tony Valente +4 more
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Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke
Antioxidants, 2022 Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain, which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc.
Lei Wang +7 more
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Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia
Journal of Diabetes Research, 2020 Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao +5 more
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Early MEK1/2 inhibition after global cerebral ischemia in rats reduces brain damage and improves outcome by preventing delayed vasoconstrictor receptor upregulation. [PDF]
PLoS ONE, 2014 BACKGROUND: Global cerebral ischemia following cardiac arrest is associated with increased cerebral vasoconstriction and decreased cerebral blood flow, contributing to delayed neuronal cell death and neurological detriments in affected patients.
Sara Ellinor Johansson +3 more
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Neural Regeneration Research, 2015 Recent evidence has suggested the neuroprotective effects of physical exercise on cerebral ischemic injury. However, the role of physical exercise in cerebral ischemia-induced hippocampal damage remains controversial.
Nabi Shamsaei +4 more
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Neuroprotective effect of baicalin on focal cerebral ischemia in rats
Neural Regeneration Research, 2018 Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease.
Jiong Dai +8 more
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Neural Regeneration Research, 2015 The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia.
Ya-yun Yan +7 more
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