Results 61 to 70 of about 1,244,067 (429)

Unsupervised Non Linear Dimensionality Reduction Machine Learning methods applied to Multiparametric MRI in cerebral ischemia: Preliminary Results [PDF]

Proceedings of the SPIE, Volume 9034, id. 90342O 9 pp. (2014), 2016
The evaluation and treatment of acute cerebral ischemia requires a technique that can determine the total area of tissue at risk for infarction using diagnostic magnetic resonance imaging (MRI) sequences. Typical MRI data sets consist of T1- and T2-weighted imaging (T1WI, T2WI) along with advanced MRI parameters of diffusion-weighted imaging (DWI) and ...
arxiv   +1 more source

Transcranial Doppler Versus CT-Angiography for Detection of Cerebral Vasospasm in Relation to Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage:A Prospective Single-Center Cohort Study: The Transcranial doppler and CT-angiography for Investigating Cerebral vasospasm in Subarachnoid hemorrhage (TACTICS) study [PDF]

, 2019
Cerebral vasospasm in the first 2 weeks after aneurysmal subarachnoid hemorrhage is recognized as a major predictor of delayed cerebral ischemia. The routine screening for cerebral vasospasm with either transcranial Doppler or CT angiography has been ...
Al-Tamimi, Anderson, Aralasmak, Banks, Binaghi, Charpentier, Connolly, Dankbaar, Dankbaar, Dankbaar, de Oliveira Manoel, Ferguson, Fisher, Frontera, Frontera, Greenberg, Hop, Ionita, Kaufmann, Kirsch, Kistka, Kumar, Malhotra, Maslehaty, Mastantuono, Naqvi, Naval, Schmidt, Suhardja, Teasdale, van Gijn, Vergouwen, Wardlaw, Washington, Willinsky, Yokose   +35 more
core   +1 more source

Proteostasis During Cerebral Ischemia [PDF]

Frontiers in Neuroscience, 2019
Cerebral ischemic is a complex pathology involving a cascade of cellular mechanisms, which deregulate proteostasis and lead to neuronal death. Proteostasis refers to the equilibrium between protein synthesis, folding, transport, and protein degradation.
Audrey M. Thiebaut, Elodie Hedou, Stefan J. Marciniak, Stefan J. Marciniak, Denis Vivien, Denis Vivien, Benoit D. Roussel   +6 more
openaire   +3 more sources

The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review

Aging and Disease, 2017
Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease. Enhancing the prevention and control of ischemic stroke is particularly important.
Wei Liang, Xiaobo Huang, Wen-qiang Chen
semanticscholar   +1 more source

The role of SUMOylation in cerebral hypoxia and ischemia [PDF]

, 2017
The process of protein modification by adding or detaching small ubiquitin-like modifiers (SUMO) proteins, called SUMOylation, contributes to the regulation of numerous processes in eukaryotic cells.
Boltze, Johannes, Peters, Myriam, Wielsch, Betty   +2 more
core   +1 more source

Pathophysiology of Cerebral Ischemia

Neurologia medico-chirurgica, 1998
The purpose of this manuscript is to briefly review the pathophysiology of cerebral ischemia. Ischemic thresholds are well-defined in lower animals. The concept of the ischemic penumbra may include regions of brain around deeper regions of ischemia but has also been defined in terms of brain salvageable by reperfusion or by pharmacological therapies ...
R. Loch Macdonald, Marcus A. Stoodley
openaire   +3 more sources

Epigenetic Mechanisms in Cerebral Ischemia [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2013
Treatment efficacy for ischemic stroke represents a major challenge. Despite fundamental advances in the understanding of stroke etiology, therapeutic options to improve functional recovery remain limited. However, growing knowledge in the field of epigenetics has dramatically changed our understanding of gene regulation in the last few decades ...
Andreas Meisel, Stefanie Märschenz, Sophie Schweizer   +2 more
openaire   +3 more sources

TREM2 protects against cerebral ischemia/reperfusion injury

Molecular Brain, 2017
Although post-ischemic inflammation induced by the innate immune response is considered an essential step in the progression of cerebral ischemia injury, the role of triggering receptor expressed on myeloid cells 2 (TREM2) in the pathogenesis of ischemic
Rong Wu, Xiang-pen Li, Pengfei Xu, Likui Huang, Jinping Cheng, Xiaolong Huang, Jingru Jiang, Long-Jun Wu, Yamei Tang   +8 more
semanticscholar   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention

Neural Regeneration Research
Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury. Various calcium channels are involved in cerebral ischemia/reperfusion injury. Cav3.2 channel is a main subtype of T-type calcium channels.
Feibiao Dai, Chengyun Hu, Xue Li, Zhetao Zhang, Hongtao Wang, Wanjun Zhou, Jiawu Wang, Qingtian Geng, Yongfei Dong, Chaoliang Tang   +9 more
doaj   +1 more source