Results 121 to 130 of about 1,618,966 (304)

The effect of estrogen therapy on cerebral metabolism in diabetic female rats. [PDF]

Comput Struct Biotechnol J, 2023
Wu CY, Lin YH, Hsieh HH, Chung YH, Hsu ST, Peng SL.   +5 more
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Basal cerebral blood volume during the poststimulation undershoot in BOLD MRI of the human brain

, 2010
One of the characteristics of the blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) response to functional challenges of the brain is the poststimulation undershoot, which has been suggested to originate from a delayed recovery ...
Merboldt, K., Frahm, Jens, Schuetze, Gunther, Helms, Gunther, Gunther Helms, Jens Frahm, Klaus Dietmar Merboldt, Helms, Gunther,, Schuetze, G., Helms, G., Merboldt, Klaus-Dietmar, Peter Dechent, Frahm, J., Dechent, Peter, Gunther Schütze, Dechent, P., Lund University.   +16 more
core   +1 more source

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

Cerebral Lactate Metabolism After Traumatic Brain Injury.

, 2016
Cerebral energy dysfunction has emerged as an important determinant of prognosis following traumatic brain injury (TBI). A number of studies using cerebral microdialysis, positron emission tomography, and jugular bulb oximetry to explore cerebral ...
Suys, T., Carteron, L., Oddo, M., Patet, C., Oddo M, Suys T, Carteron L, Patet C   +7 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Guía de orientación para familiares, amistades y personas que ejercen los cuidados de personas con daño cerebral adquirido [PDF]

Esta guía está dirigida a familiares, amigos y cuidadores de personas con daño cerebral. El texto ofrece indicaciones sencillas sobre las diferentes etapas en la evolución del daño cerebral desde los primeros momentos de la lesión y pretende servir de ...
Daño Cerebral Estatal
core  

Cerebral energy metabolism during induced mitochondrial dysfunction

, 2012
In patients with traumatic brain injury as well as stroke, impaired cerebral oxidative energy metabolism may be an important factor contributing to the ultimate degree of tissue damage.
Olsen, Niels Vidiendal, Nordström, C H, Pedersen, S M, Bindslev, TT, Olsen, N V, Toft, P, Nielsen, T H, Bindslev, T T   +7 more
core   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism

Molecular Brain
Amyloid-β42 (Aβ42) regulates synaptic plasticity and memory formation at physiological levels in the brain, but in Alzheimer’s disease (AD), it can disrupt brain function and glucose metabolism.
Ali Azargoonjahromi, Hamide Nasiri, for the Alzheimer’s Disease Neuroimaging Initiative#   +2 more
doaj   +1 more source