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Research progress of impaired cerebral hemodynamics in cerebral small vessel disease

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Cerebral hemodynamic damage is an important mechanism in the pathogenesis of arteriolosclerotic cerebral small vessel disease (CSVD). The hemodynamic damage of cerebral small vessel disease includes the changes of blood pressure variability (BPV ...
LIU Na   +5 more
doaj   +1 more source

Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes

open access: yesBMJ Open Diabetes Research & Care, 2021
Introduction Cerebral small-vessel disease is common in neurologically asymptomatic individuals with type 1 diabetes. The retinal vasculature is thought to mirror the brain’s vasculature, but data on this association are limited in type 1 diabetes.
Turgut Tatlisumak   +10 more
doaj   +1 more source

Genetics of Cerebral Small Vessel Disease [PDF]

open access: yesJournal of Stroke, 2015
Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive impairment among the elderly and is a more frequent cause of stroke in Asia than in the US or Europe.
Jay Chol Choi
doaj   +1 more source

HTRA1-related autosomal dominant cerebral small vessel disease

open access: yesChinese Medical Journal, 2021
. Background. Homozygous or compound heterozygous mutations in high temperature requirement serine peptidase A1 (HTRA1) gene are responsible for cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL ...
Jing-Yi Liu   +8 more
doaj   +1 more source

Cerebral Small Vessel Disease

open access: yesCell Transplantation, 2018
Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies.
Qian Li   +6 more
doaj   +1 more source

Surface-based morphometry of the cerebral cortex in cognitive impairments of varying severity in patients with age-related cerebral small vessel disease [PDF]

open access: yesDigital Diagnostics
BACKGROUND: Analysis of structural magnetic resonance images is essential to assessing the main substrate of cognitive impairment in sporadic age-related cerebral small vessel disease, accounting for up to 45% of all dementia cases.
Elena I. Kremneva   +7 more
doaj   +1 more source

Cerebral Small Vessel Disease and Chronic Kidney Disease [PDF]

open access: yesJournal of Stroke, 2015
Chronic kidney disease, defined by a decreased glomerular filtration rate or albuminuria, is recognized as a major global health burden, mainly because it is an established risk factor for cardiovascular and cerebrovascular diseases. The magnitude of the
Kazunori Toyoda
doaj   +1 more source

Clinical practice guideline for cognitive impairment of cerebral small vessel disease

open access: yesAging Medicine, 2019
Cognitive impairment of cerebral small vessel disease (CSVD) is one of the most common cognitive disorders. It has a high incidence and results in heavy social burden; thus, it is essential to provide reasonable diagnosis and treatment in clinical ...
Dantao Peng   +2 more
doaj   +1 more source

Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the “ZOOM@SVDs” study

open access: yesCerebral Circulation - Cognition and Behavior, 2021
Background: Cerebral small vessel diseases (SVDs) are a major cause of stroke and dementia. Yet, specific treatment strategies are lacking in part because of a limited understanding of the underlying disease processes.
Hilde van den Brink   +16 more
doaj   +1 more source

Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial

open access: yesFrontiers in Pharmacology, 2023
Background: Hypertensive cerebral small vessel disease (HT-CSVD) is a cerebrovascular clinical, imaging and pathological syndrome caused by hypertension (HT). The condition manifests with lesions in various vessels including intracranial small/arterioles,
Rui Fang   +30 more
doaj   +1 more source

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