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Genetics of Cerebral Small Vessel Disease [PDF]

Journal of Stroke, 2015
Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive impairment among the elderly and is a more frequent cause of stroke in Asia than in the US or Europe.
Jay Chol Choi
doaj   +3 more sources

Current pathophysiological concepts in Cerebral Small Vessel Disease [PDF]

Frontiers in Aging Neuroscience, 2014
The association between cerebral small vessel disease (SVD) – in the form of white matter lesions, infarctions, and hemorrhages – with vascular cognitive impairment (VCI), has mostly been deduced from observational studies.
Fred eRincon, Clinton eWright
doaj   +4 more sources

Association between homocysteine and severe cerebral small vessel disease burden in patients with type 2 diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Huang W, Jie H, Yi J, Liu Q, Li S, Luo Y, Tang S, Chi Z, Wu C.   +8 more
europepmc   +3 more sources

Research progress of impaired cerebral hemodynamics in cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Cerebral hemodynamic damage is an important mechanism in the pathogenesis of arteriolosclerotic cerebral small vessel disease (CSVD). The hemodynamic damage of cerebral small vessel disease includes the changes of blood pressure variability (BPV ...
LIU Na, XUE Yang, TANG Jie, ZHANG Miao⁃yi, REN Xue , FU Jian⁃hui   +5 more
doaj   +1 more source

Cerebral small-vessel disease is associated with the severity of diabetic retinopathy in type 1 diabetes

BMJ Open Diabetes Research & Care, 2021
Introduction Cerebral small-vessel disease is common in neurologically asymptomatic individuals with type 1 diabetes. The retinal vasculature is thought to mirror the brain’s vasculature, but data on this association are limited in type 1 diabetes.
Turgut Tatlisumak, Jukka Putaala, Daniel Gordin, Paula Summanen, Carol Forsblom, Per-Henrik Groop, Juha Martola, Marika I Eriksson, Sara Shams, Ron Liebkind, Lena M Thorn   +10 more
doaj   +1 more source

Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]

, 2001
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes, Bertsch, Thomas, Casarin, Wendy, Fassbender, Klaus, Höly, Sabine, Kuehl, Sandra, Mielke, Orell, Muehlhauser, Frank, Ragoschke, Andreas, Walter, Silke, Zimmer, Wilma   +10 more
core   +1 more source

NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]

, 2012
Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.
Allili, Nassira, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Herve, Dominique, Jouvent, Eric, Yao, Ming   +6 more
core   +1 more source

HTRA1-related autosomal dominant cerebral small vessel disease

Chinese Medical Journal, 2021
. Background. Homozygous or compound heterozygous mutations in high temperature requirement serine peptidase A1 (HTRA1) gene are responsible for cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL ...
Jing-Yi Liu, Yi-Cheng Zhu, Li-Xin Zhou, Yan-Ping Wei, Chen-Hui Mao, Li-Ying Cui, Bin Peng, Ming Yao, Xin Chen   +8 more
doaj   +1 more source

CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]

, 2002
Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
core   +1 more source

Acute Paraplegia with Cognitive Alterations After Bilateral Infarcts in Cerebral Small Vessel Disease [PDF]

, 2017
Cerebral small vessel disease (SVD) affects the small arteries, arterioles, venules and capillaries in the brain and can be identified clinically and/or radiologically.
Forteza, Francisco Javier Ros
core   +2 more sources