Imaging scoring methods for cerebral small vessel disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2023 The pathogenesis of cerebral small vessel disease (CSVD) is not yet clear, and there is no effective treatment method at present. MRI is an important imaging in diagnosing.
PAN Xi⁃juan +2 more
doaj +1 more source
Improving blood vessel tortuosity measurements via highly sampled numerical integration of the Frenet-Serret equations [PDF]
, 2019 Measures of vascular tortuosity--how curved and twisted a vessel is--are associated with a variety of vascular diseases. Consequently, measurements of vessel tortuosity that are accurate and comparable across modality, resolution, and size are greatly needed.
arxiv +1 more source
Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease
Nature Network Boston, 2021 Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia.
Marie-Gabrielle Duperron +88 more
semanticscholar +1 more source
Sex Differences in Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis
Frontiers in Neurology, 2021 Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild cognitive impairment, dementia and physical impairments. Differences in SVD incidence or severity between males and females are unknown.
Lorena Jiménez-Sánchez +7 more
semanticscholar +1 more source
PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice [PDF]
, 2021 Recently, several genome-wide association studies identified PHACTR1 as key locus for five diverse vascular disorders: coronary artery disease, migraine, fibromuscular dysplasia, cervical artery dissection and hypertension.
Alonso, Isabel +33 more
core +1 more source
Come together over me: Cells that form the dermatocranium and chondrocranium in mice
The Anatomical Record, EarlyView., 2023 Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri +5 more
wiley +1 more source
Where is VALDO? VAscular Lesions Detection and segmentatiOn challenge at MICCAI 2021 [PDF]
arXiv, 2022 Imaging markers of cerebral small vessel disease provide valuable information on brain health, but their manual assessment is time-consuming and hampered by substantial intra- and interrater variability. Automated rating may benefit biomedical research, as well as clinical assessment, but diagnostic reliability of existing algorithms is unknown.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Exploring the prevalence and association between intracranial atherosclerosis (ICAS) and cerebral small vessel diseases (CSVD), this study delved beyond the current scope, utilising high‐resolution vessel wall MRI (HRVW‐MRI) to investigate how subtle changes in intracranial atherosclerotic features influence the various burdens of ...
Joseph Amihere Ackah +6 more
wiley +1 more source
Small vessel disease burden and functional brain connectivity in mild cognitive impairment [PDF]
Background: The role of small vessel disease in the development of dementia is not yet completely understood. Functional brain connectivity has been shown to differ between individuals with and without cerebral small vessel disease.
Biessels, Geert-Jan +12 more
core +8 more sources
Dual‐Phase C‐11 PiB PET Images for Detecting Tau Pathology in Cerebral Amyloid Angiopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Cerebral amyloid angiopathy (CAA) is a major cause of lobar intracerebral hemorrhage and cognitive dysfunction in the elderly, and frequently coexists with Alzheimer's disease and tau pathology. Dual‐phase 11C‐PiB PET detects amyloid deposition and cerebral perfusion changes and may have diagnostic value for identifying tau in CAA ...
Meng‐Ting Chiang +4 more
wiley +1 more source