Results 41 to 50 of about 211,077 (381)

Inflammatory biomarkers and cerebral small vessel disease: a community-based cohort study

Stroke and vascular neurology, 2022
Background and purpose Although inflammation has been proposed to be a candidate risk factor for cerebral small vessel disease (CSVD), previous findings remain largely inconclusive and vary according to disease status and study designs. The present study
Dingding Zhang, Yuan Cao, Jingwei Mu, Yiming Liu, F. Gao, F. Han, F. Zhai, Li-xin Zhou, J. Ni, M. Yao, Ming-Li Li, Z. Jin, Shu-yang Zhang, L. Cui, Yong Shen, Yicheng Zhu   +15 more
semanticscholar   +1 more source

Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment [PDF]

, 2023
Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain barrier impairments which play a key role in the development of white matter lesions.
Ahmed, Zubair, Backes, Walter H., Blankesteijn, W. Matthijs, Caiment, Florian, Foulquier, Sébastien, Fulton, Daniel, Jansen, Jacobus F. A., Leenders, Peter, Majcher, Daria, Manukjan, Narek, Smeets, Hubert J., Staals, Julie, Suidgeest, Ernst, van der Weerd, Louise, van Herwijnen, Marcel, van Oostenbrugge, Robert J., Vanmierlo, Tim   +16 more
core   +2 more sources

The global burden of cerebral small vessel disease in low- and middle-income countries: A systematic review and meta-analysis

International Journal of Stroke, 2022
Background: Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. Previous studies on the prevalence of cSVD are mostly based on single geographically defined cohorts in high-income countries.
B. Lam, Yuan Cai, R. Akinyemi, G. Biessels, H. van den Brink, Christopher L H Chen, Chin Wai Cheung, King Ngai Chow, Henry Kh Chung, M. Duering, Siu Ting Fu, Deb Gustafson, S. Hilal, Vincent Ming Ho Hui, R. Kalaria, Sangyun Kim, M. Lam, F. de Leeuw, A. Li, H. Markus, A. Marseglia, Huijing Zheng, J. O'Brien, L. Pantoni, P. Sachdev, E. Smith, J. Wardlaw, Vincent C T Mok   +27 more
semanticscholar   +1 more source

Large-vessel correlates of cerebral small-vessel disease [PDF]

Neurology, 2013
Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease.The study comprised 1,800 participants (aged 72.5 ± 4.1 years, 59.4% women) from the 3C-Dijon Study, a population-based, prospective cohort study, who had undergone quantitative brain MRI and carotid ultrasound.
Pierre Boutouyrie, Mahmoud Zureik, Christophe Tzourio, Christophe Tzourio, Sabrina Schilling, Bernard Mazoyer, Fernando Pico, Yi-Cheng Zhu, Yi-Cheng Zhu, Marion Brisset, Stéphane Laurent, Carole Dufouil, Carole Dufouil, Stéphanie Debette, Stéphanie Debette   +14 more
openaire   +4 more sources

NIHSS Scores in Ischemic Small Vessel Disease: A Study in CADASIL [PDF]

, 2012
Background: The National Institutes of Health Stroke Scale (NIHSS) is widely used to measure neurological deficits, evaluate the effectiveness of treatment and predict outcome in acute ischemic stroke.
Allili, Nassira, Chabriat, Hugues, Dichgans, Martin, Duering, Marco, Herve, Dominique, Jouvent, Eric, Yao, Ming   +6 more
core   +1 more source

Advances in the Role of Endothelial Cells in Cerebral Small Vessel Disease

Frontiers in Neurology, 2022
Cerebral small vessel disease (CSVD) poses a serious socio-economic burden due to its high prevalence and severe impact on the quality of life of elderly patients.
T. Bai, Shijia Yu, Juan Feng
semanticscholar   +1 more source

CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]

, 2002
Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
core   +1 more source

The Underlying Role of the Glymphatic System and Meningeal Lymphatic Vessels in Cerebral Small Vessel Disease

Biomolecules, 2022
There is a growing prevalence of vascular cognitive impairment (VCI) worldwide, and most research has suggested that cerebral small vessel disease (CSVD) is the main contributor to VCI. Several potential physiopathologic mechanisms have been proven to be
Yu-Syuan Tian, Mengxi Zhao, Yiyi Chen, Mo Yang, Yilong Wang   +4 more
semanticscholar   +1 more source

Acute Paraplegia with Cognitive Alterations After Bilateral Infarcts in Cerebral Small Vessel Disease [PDF]

, 2017
Cerebral small vessel disease (SVD) affects the small arteries, arterioles, venules and capillaries in the brain and can be identified clinically and/or radiologically.
Forteza, Francisco Javier Ros
core   +2 more sources

Surface-based morphometry of the cerebral cortex in cognitive impairments of varying severity in patients with age-related cerebral small vessel disease [PDF]

Digital Diagnostics
BACKGROUND: Analysis of structural magnetic resonance images is essential to assessing the main substrate of cognitive impairment in sporadic age-related cerebral small vessel disease, accounting for up to 45% of all dementia cases.
Elena I. Kremneva, Larisa A. Dobrynina, Kamila V. Shamtieva, Victoria V. Trubitsyna, Zukhra S. Gadzhieva, Angelina G. Makarova, Maria M. Tsypushtanova, Marina V. Krotenkova   +7 more
doaj   +1 more source