Results 51 to 60 of about 435,514 (353)

Surface-based morphometry of the cerebral cortex in cognitive impairments of varying severity in patients with age-related cerebral small vessel disease [PDF]

Digital Diagnostics
BACKGROUND: Analysis of structural magnetic resonance images is essential to assessing the main substrate of cognitive impairment in sporadic age-related cerebral small vessel disease, accounting for up to 45% of all dementia cases.
Elena I. Kremneva, Larisa A. Dobrynina, Kamila V. Shamtieva, Victoria V. Trubitsyna, Zukhra S. Gadzhieva, Angelina G. Makarova, Maria M. Tsypushtanova, Marina V. Krotenkova   +7 more
doaj   +1 more source

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

Current Opinion in Neurology, 2021
Purpose of review We present recent developments in the field of small vessel disease (SVD)-related vascular cognitive impairment, including pathological mechanisms, updated diagnostic criteria, cognitive profile, neuroimaging markers and risk factors ...
M.C. Zanon Zotin, L. Sveikata, A. Viswanathan, P. Yilmaz   +3 more
semanticscholar   +1 more source

Blood pressure gradients in cerebral arteries: A clue to pathogenesis of cerebral small vessel disease [PDF]

, 2017
Rationale: The role of hypertension in cerebral small vessel disease is poorly understood. At the base of the brain (the \u27vascular centrencephalon\u27), short straight arteries transmit blood pressure directly to small resistance vessels; the cerebral
Blanco, Pablo J., Müller, Lucas O., Spence, J. David   +2 more
core   +2 more sources

Clinical practice guideline for cognitive impairment of cerebral small vessel disease

Aging Medicine, 2019
Cognitive impairment of cerebral small vessel disease (CSVD) is one of the most common cognitive disorders. It has a high incidence and results in heavy social burden; thus, it is essential to provide reasonable diagnosis and treatment in clinical ...
Dantao Peng, Geriatric Neurology Group, Chinese Society of Geriatrics, Clinical Practice Guideline for Cognitive Impairment of Cerebral Small Vessel Disease Writing Group   +2 more
doaj   +1 more source

Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial

Frontiers in Pharmacology, 2023
Background: Hypertensive cerebral small vessel disease (HT-CSVD) is a cerebrovascular clinical, imaging and pathological syndrome caused by hypertension (HT). The condition manifests with lesions in various vessels including intracranial small/arterioles,
Rui Fang, Rui Fang, Hua Hu, Yue Zhou, Shanshan Wang, Zhigang Mei, Ruining She, Xiwen Peng, Qiling Jiang, Xiangyuan Wang, Le Xie, Hongyuan Lin, Pan Meng, Kun Zhang, Wei Wang, Yao Xie, Litao Liu, Litao Liu, Jiao Tong, Dahua Wu, Yunhua Luo, Chang Liu, Yifang Lu, Shangzhen Yu, Shaowu Cheng, Linyong Xu, Zhuyuan Fang, Hongcai Shang, Hongcai Shang, Jinwen Ge, Jinwen Ge   +30 more
doaj   +1 more source

Gait in Elderly With Cerebral Small Vessel Disease [PDF]

Stroke, 2010
Background and Purpose— Gait disorders are common in the elderly and are related to loss of functional independence and death. White matter lesions (WMLs) may be related, but only a minority of individuals with WMLs has gait disorders.
de Laat, K.F., van Norden, A.G.W., Gons, R.A.R., van Oudheusden, L.J.B., van Uden, I.W.M., Bloem, B.R., Zwiers, M.P., Zwiers, M.P., de Leeuw, F.E.   +8 more
openaire   +4 more sources

A pilot randomized controlled trial of WeiNaoKang (SaiLuoTong) in treating vascular dementia

AGING MEDICINE, Volume 5, Issue 4, Page 246-256, December 2022., 2022
A 16‐week randomized double‐blind, placebo‐controlled trial for vascular dementia was carried out with WeiNaoKang (or SaiLuoTong). There were significant differences in improvement in cognitive function and activities of daily living, favouring the treatment group.
Junguang Liu, Dennis Chang, Dennis Cordato, Kien Lee, Hugh Dixson, Alan Bensoussan, Daniel Kam Yin Chan   +6 more
wiley   +1 more source

Retinal biomarkers of Cerebral Small Vessel Disease: A systematic review

PLoS ONE, 2022
Introduction Cerebral Small Vessel Disease (CSVD), a progressive degenerative disorder of small caliber cerebral vessels, represents a major contributor to stroke and vascular dementia incidence worldwide.
Elena Biffi, Zachary Turple, Jessica A Chung, A. Biffi   +3 more
semanticscholar   +1 more source

Plasma inflammatory biomarkers in cerebral small vessel disease: A review

CNS Neuroscience & Therapeutics, 2022
Cerebral small vessel disease (CSVD) is a group of pathological processes affecting small arteries, arterioles, capillaries, and small veins of the brain.
Shuling Wan, Chaitu Dandu, Guangyu Han, Yi-bing Guo, Yuchuan Ding, Haiqing Song, R. Meng   +6 more
semanticscholar   +1 more source

A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease [PDF]

Trends in Neurosciences, 2021
The blood vessels of the brain are lined with endothelial cells and it has been long known that these help to regulate blood flow to the brain. However, there is increasing evidence that these cells also interact with the surrounding brain tissue. These interactions change when the endothelial cells become dysfunctional and have an impact in diseases ...
Quick, S, Moss, J, Rajani, RM, Williams, A   +3 more
openaire   +5 more sources