Results 51 to 60 of about 211,077 (381)

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

Current Opinion in Neurology, 2021
Purpose of review We present recent developments in the field of small vessel disease (SVD)-related vascular cognitive impairment, including pathological mechanisms, updated diagnostic criteria, cognitive profile, neuroimaging markers and risk factors ...
M.C. Zanon Zotin, L. Sveikata, A. Viswanathan, P. Yilmaz   +3 more
semanticscholar   +1 more source

Common NOTCH3 Variants and Cerebral Small-Vessel Disease. [PDF]

, 2015
BACKGROUND AND PURPOSE: The most common monogenic cause of cerebral small-vessel disease is cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, caused by NOTCH3 gene mutations.
Adib-Samii, Poneh, Bevan, Steve, Boncoraglio, Giorgio, Dichgans, Martin, Hassan, Ahamad, Levi, Christopher, Markus, Hugh S, Meschia, James, Rosand, Jonathan, Rost, Natalia S, Rothwell, Peter M, Rutten-Jacobs, Loes CA, Sudlow, Cathie, Thijs, Vincent, Traylor, Matthew   +14 more
core   +2 more sources

Efficacy and safety of naotaifang capsules for hypertensive cerebral small vessel disease: Study protocol for a multicenter, randomized, double-blind, placebo-controlled clinical trial

Frontiers in Pharmacology, 2023
Background: Hypertensive cerebral small vessel disease (HT-CSVD) is a cerebrovascular clinical, imaging and pathological syndrome caused by hypertension (HT). The condition manifests with lesions in various vessels including intracranial small/arterioles,
Rui Fang, Rui Fang, Hua Hu, Yue Zhou, Shanshan Wang, Zhigang Mei, Ruining She, Xiwen Peng, Qiling Jiang, Xiangyuan Wang, Le Xie, Hongyuan Lin, Pan Meng, Kun Zhang, Wei Wang, Yao Xie, Litao Liu, Litao Liu, Jiao Tong, Dahua Wu, Yunhua Luo, Chang Liu, Yifang Lu, Shangzhen Yu, Shaowu Cheng, Linyong Xu, Zhuyuan Fang, Hongcai Shang, Hongcai Shang, Jinwen Ge, Jinwen Ge   +30 more
doaj   +1 more source

Gait in Elderly With Cerebral Small Vessel Disease [PDF]

Stroke, 2010
Background and Purpose— Gait disorders are common in the elderly and are related to loss of functional independence and death. White matter lesions (WMLs) may be related, but only a minority of individuals with WMLs has gait disorders.
de Laat, K.F., van Norden, A.G.W., Gons, R.A.R., van Oudheusden, L.J.B., van Uden, I.W.M., Bloem, B.R., Zwiers, M.P., Zwiers, M.P., de Leeuw, F.E.   +8 more
openaire   +4 more sources

Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study. [PDF]

, 2013
Small vessel disease (mainly hypertensive arteriopathy and cerebral amyloid angiopathy (CAA)) is an important cause of spontaneous intracerebral haemorrhage (ICH), a devastating and still poorly understood stroke type. Enlarged perivascular spaces (EPVS)
Baron, JC, Charidimou, A, Fox, Z, Jäger, HR, Laloux, P, Meegahage, R, Peeters, A, Vandermeeren, Y, Werring, DJ   +8 more
core   +1 more source

Clinical practice guideline for cognitive impairment of cerebral small vessel disease

Aging Medicine, 2019
Cognitive impairment of cerebral small vessel disease (CSVD) is one of the most common cognitive disorders. It has a high incidence and results in heavy social burden; thus, it is essential to provide reasonable diagnosis and treatment in clinical ...
Dantao Peng, Geriatric Neurology Group, Chinese Society of Geriatrics, Clinical Practice Guideline for Cognitive Impairment of Cerebral Small Vessel Disease Writing Group   +2 more
doaj   +1 more source

Association between arterial stiffness, cerebral small vessel disease and cognitive impairment: A systematic review and meta-analysis [PDF]

, 2015
Arterial stiffness may be a cause of cerebral small vessel disease and cognitive impairment. We therefore performed a systematic review and meta-analysis of studies on the association between stiffness, cerebral small vessel disease and cognitive ...
Henry, Ronald M. A., Launer, Lenore J., Protogerou, Athanase D., Schram, Miranda T., Stehouwer, Coen D. A., van Sloten, Thomas T.   +5 more
core   +1 more source

Targeting Cerebral Small Vessel Disease With MRI [PDF]

Stroke, 2017
Cerebral small vessel disease (SVD) is a severely debilitating disease affecting the smallest vessels in the brain. It is a major cause of cognitive decline, dementia, and functional disability in the elderly, and it is also responsible for ≈25% of all cerebral strokes.1,2 Still, treatment options are restricted to preventive risk management because ...
Zwanenburg, J.J.M., Osch, M.J.P. van
openaire   +3 more sources

A Vessel for Change: Endothelial Dysfunction in Cerebral Small Vessel Disease [PDF]

Trends in Neurosciences, 2021
The blood vessels of the brain are lined with endothelial cells and it has been long known that these help to regulate blood flow to the brain. However, there is increasing evidence that these cells also interact with the surrounding brain tissue. These interactions change when the endothelial cells become dysfunctional and have an impact in diseases ...
Quick, S, Moss, J, Rajani, RM, Williams, A   +3 more
openaire   +5 more sources

Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study. [PDF]

, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Garcia, Melissa E, Gudnason, Vilmundur, Harris, Tamara B, Henry, Ronald M A, Jonsson, Palmi V, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F, Sigurdsson, Sigurdur, Stehouwer, Coen D A, van Buchem, Mark A, van Sloten, Thomas T   +11 more
core   +1 more source