Background The triglyceride-glucose (TyG) index is a marker of insulin resistance (IR) and has been associated with various metabolic syndromes, cardiovascular diseases, and cerebrovascular diseases.
Ki-Woong Nam+5 more
semanticscholar +1 more source
Alzheimer and vascular brain disease: Senile dementia. [PDF]
Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases.
Engelhardt, Eliasz, Grinberg, Lea T
core +2 more sources
MRI Visualization of Whole Brain Macro- and Microvascular Remodeling in a Rat Model of Ischemic Stroke: A Pilot Study [PDF]
Using superparamagnetic iron oxide nanoparticles (SPION) as a single contrast agent, we investigated dual contrast cerebrovascular magnetic resonance imaging (MRI) for simultaneously monitoring macro- and microvasculature and their association with ...
Cho, Hyungjoon+3 more
core +1 more source
Multi‐Scale Modeling of a 3D Soft Magnetoelectric Patch for Wireless Nerve Stimulation
Core‐shell, magnetoelectric nanoparticles (MENPs) can serve as wireless electric nano‐sources, thanks to their ability to generate high levels of electricity, when stimulated by a human‐safe external magnetic field. By combining MENPs with soft, biocompatible polymeric matrices and optimizing its composite configuration and electrical behavior via ...
Giulia Suarato+6 more
wiley +1 more source
Eosinophilic granulomatosis with polyangiitis (EGPA) and PRES: a case-based review of literature in ANCA-associated vasculitides [PDF]
Eosinophilic granulomatosis with polyangiitis (EGPA) is a small-sized vessel systemic necrotizing vasculitis and belongs to the family of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
Barilaro, Giuseppe+3 more
core +1 more source
Flow Analysis in Pathological Microvascular Models by Ultrasound Localization Microscopy
This study presents a new platform combining ultrasound localization microscopy with biomimetic gelatin phantoms to analyze flow dynamics in small vessels with narrowing or obstructions. Using microbubble tracking, the method enables high‐resolution velocity mapping in 100–500 µm channels, revealing flow changes in pathological microvascular conditions
Yarin Gershman+3 more
wiley +1 more source
Increasing evidence suggests a role for endothelial cell (EC) dysfunction in pathogenesis of cerebral small vessel disease. Commonly used medications including certain antihypertensives and statins have EC-stabilizing effects.
Charlotte Elisabeth Becker+3 more
doaj +1 more source
Rapidly Progressing Neurocognitive Disorder in a Male with FXTAS and Alzheimer's Disease. [PDF]
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder that usually begins in the early 60s and affects carriers of premutation expansion (55-200 CGG repeats) of the fragile X mental retardation 1 (FMR1) gene.
Aydin, Elber Yuksel+8 more
core +2 more sources
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source
Nicotinamide riboside rescues angiotensin II–induced cerebral small vessel disease in mice
Hypertension is a leading cause of cerebral small vessel disease (CSVD). Currently, treatments for CSVD are limited. Nicotinamide riboside (NR) can protect against vascular injury and cognitive impairment in neurodegenerative diseases. In this study, the
Chengcheng Li+10 more
semanticscholar +1 more source