Results 101 to 110 of about 98,582 (280)

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

Frontiers in Aging Neuroscience, 2020
Pericytes are unique, multi-functional mural cells localized at the abluminal side of the perivascular space in microvessels. Originally discovered in 19th century, pericytes had drawn less attention until decades ago mainly due to lack of specific ...
Maiko T. Uemura, Maiko T. Uemura, Takakuni Maki, Masafumi Ihara, Virginia M. Y. Lee, John Q. Trojanowski   +5 more
doaj   +1 more source

Alcohol Consumption and Cerebral Small- and Large-Vessel Diseases: A Mendelian Randomization Analysis [PDF]

Aims: It remains inconclusive regarding alcohol intake and stroke risk because determining risk factors depends on the specific pathogenesis of stroke. We used the variant rs671 in the aldehyde dehydrogenase 2 gene (ALDH2) as an instrument to investigate
矢野, 裕一朗, KADOTA, Aya, 0000-0001-6203-9339, NOZAKI, Kazuhiko, 156, 0000-0002-2565-7290, 1213, トリイ, サユキ, 7651, 00324567, 7377, OKAMURA, Tomonori, オカムラ, トモノリ, タバラ, ヤスハル, 70144483, 0000-0001-7378-0544, ヒサマツ, タカシ, 久松, 隆史, 20566567, 0000-0003-1623-068X, 鳥居, さゆ希, 30773973, 椎野, 顯彦, TORII, Sayuki, ノザキ, カズヒコ, YANO, Yuichiro, 岡村, 智教, MIURA, Katsuyuki, 60546068, コンドウ, ケイコ, 上島, 弘嗣, UESHIMA, Hirotsugu, 50215935, 近藤, 慶子, 9083, 三浦, 克之, 3536, SHIINO, Akihiko, 0000-0002-7742-4253, 10586241, 539, 90252452, TABARA, Yasuharu, ミウラ, カツユキ, 門田, 文, 0000-0002-2646-9582, 野﨑, 和彦, ヤノ, ユウイチロウ, KONDO, Keiko, カドタ, アヤ, 90257452, シイノ, アキヒコ, 田原, 康玄, 6336, HISAMATSU, Takashi, ウエシマ, ヒロツグ, 2935, 1647, 1966   +58 more
core   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Optimization of Magnetic Milli‐Spinner for Robotic Endovascular Intervention

Advanced Robotics Research, EarlyView.
This work presents the design optimization of a multifunctional magnetic milli‐spinner for high‐speed propulsion and efficient clot debulking. The optimized design achieves an ultrafast swimming velocity of 55 cm/s (≈175 body lengths/s) in saline water, enabling stable upstream swimming against strong physiological flows and establishing magnetic milli‐
Lu Lu, Luca Higgins, Jack Bernardo, Ruike Renee Zhao   +3 more
wiley   +1 more source

CADASIL Affects Multiple Aspects of Cerebral Small Vessel Function on 7T-MRI [PDF]

, 2023
Objective: Cerebral small vessel diseases (cSVDs) are a major cause of stroke and dementia. We used cutting-edge 7T-MRI techniques in patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), to ...
SVDs@target group
core  

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

Advanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung, Victor Tsao, Alina D Peshkova, Oscar A. Marcos‐Contreras, Kim Ha, Brian M Dulmovits, Nkemdilim Okoli, Anvi Sinha, Gennadiy Fonar, Rong Qiu, Rolf D Bates, Janelle Yeboah, Carson Shalaby, Tyler Truex, Soomin Jeong, Edna C Hardeman, Peter W Gunning, Vladimir R Muzykantov, Jacob W Myerson, Christopher S Thom   +19 more
wiley   +1 more source

Progress of relationship between cerebral microbleeds and intracranial hemorrhage secondary to cerebral ischemic events

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Cerebral microbleeds (CMBs) are typical neuro-imaging marker of cerebral small vessel disease (cSVD), representing that some small intracranial vessels rupture have occured in the past. Correlation between CMBs and intracranial hemorrhage (ICH) secondary
Jie ZHUO
doaj