Results 91 to 100 of about 98,582 (280)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez   +75 more
wiley   +1 more source

Association Between Endothelial Cell Stabilizing Medication and Small Vessel Disease Stroke: A Case-Control Study

Frontiers in Neurology, 2019
Increasing evidence suggests a role for endothelial cell (EC) dysfunction in pathogenesis of cerebral small vessel disease. Commonly used medications including certain antihypertensives and statins have EC-stabilizing effects.
Charlotte Elisabeth Becker, Charlotte Elisabeth Becker, Terence J. Quinn, Anna Williams   +3 more
doaj   +1 more source

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source

Contribution of acute infarcts to cerebral small vessel disease progression [PDF]

, 2019
Contains fulltext : 208985.pdf (Publisher’s version ) (Open Access)OBJECTIVE: To determine the contribution of acute infarcts, evidenced by diffusion-weighted imaging positive (DWI+) lesions, to progression of white matter ...
Tuladhar, A.M., Duering, M., Benno Gesierich, Floris H. B. M. Schreuder, Wiegertjes, Kim, Norris, D.G., Leeuw, F.E. de, Gesierich, Benno, Telgte, A. ter, Schreuder, Floris H B M, Catharina J. M. Klijn, Tuladhar, Anil M., Klijn, Catharina J M, de Klerk, Jabke J, Norris, David G, de Leeuw, Frank Erik, Schreuder, F. H., Ter Telgte, Annemieke, Miguel A. Araque Caballero, Tuladhar, Anil Man, Martin Dichgans, Kim Wiegertjes, Jabke J. de Klerk, Klerk, J.J. de, de Klerk, Jabke J., Gesierich, B., Araque Caballero, M.A., Telgte, Annemieke ter, Klijn, Catharina J.M., Schreuder, Floris H.B.M., Duering, Marco, David G. Norris, Annemieke ter Telgte, Araque Caballero, Miguel A, Tuladhar, Anil M, Norris, David G., Kuijf, Hugo J, Marques, Jose P., José P. Marques, Kuijf, H.J., Araque Caballero, Miguel Angel, Klerk, J. J. de, Marco Duering, Wiegertjes, K., de Leeuw, Frank-Erik, Hugo J. Kuijf, Kuijf, H. J., Klijn, Catharina J. M., Mathias Huebner, Klijn, C.J.M., Schreuder, F.H.B.M., Anil M. Tuladhar, Araque Caballero, Miguel A., Dichgans, Martin, Huebner, M., Marques, José P, Huebner, Mathias, Marques, J.P., Dichgans, M., Kuijf, Hugo J., Frank‐Erik de Leeuw   +60 more
core   +1 more source

RESEARCH ADVANCES IN THE MECHANISM OF CEREBRAL SMALL VESSEL DISEASES IN PATIENTS WITH CORONAVIRUS DISEASE 2019

, 2023
A large number of studies have shown that severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) can cause potential harm to cerebral small blood vessels and may further lead to nervous system injury.
LIU Yue, WANG Lin, LI Ying, LAN Huifu, LI Cuiping, YANG Shaonan
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Inflammatory disorders that affect the cerebral small vessels

Chinese Medical Journal
. This comprehensive review synthesizes the latest advancements in understanding inflammatory disorders affecting cerebral small vessels, a distinct yet understudied category within cerebral small vessel diseases (SVD).
Fei Han, Siyuan Fan, Bo Hou, Lixin Zhou, Ming Yao, Min Shen, Yicheng Zhu, Joanna M. Wardlaw, Jun Ni, Ting Gao   +9 more
doaj   +1 more source

Additive Manufacturing of Patient‐Specific Intracranial Aneurysm Cell Culture Models

Advanced Materials Technologies, EarlyView.
Patient‐specific intracranial aneurysm models were fabricated using chocolate moulding, 3D printed water‐soluble cores, and direct resin 3D printing. Moulding PDMS around sacrificial cores made of chocolate or 3D printed water‐soluble resin yielded accurate, expandable, and endothelializable models that outperformed resin‐based approaches.
Chloe M. de Nys, Jaimee‐Lee Wood, James I. Novak, Danilo Carluccio, Craig D. Winter, Ashley R. Murphy, Mark C. Allenby   +6 more
wiley   +1 more source

Cerebral small vessel disease and Alzheimer’s disease

, 2015
Zhiyou Cai,1 Chuanling Wang,1 Wenbo He,1 Hanjun Tu,2 Zhengang Tang,3 Ming Xiao,4 Liang-Jun Yan51Department of Neurology, Renmin Hospital, Hubei University of Medicine, 2Department of Basic Research Center, Hubei University of Medicine, 3Department of ...
Yan LJ, Tang Z, Xiao M, Wang C, He W, Cai Z, Tu H   +6 more
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