Results 191 to 200 of about 212,620 (328)
Annals of Neurology, EarlyView.Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh +4 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Endovascular thrombectomy (EVT) is increasingly used for pediatric large vessel occlusion (LVO) stroke, however, its role in isolated M2 occlusions remains underexplored. This study compared clinical outcomes in children with isolated M2 occlusion treated with EVT versus best medical therapy (BMT). Methods This multicenter cohort study pooled
Peter B. Sporns +24 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Aneurysm wall enhancement (AWE) may predict aneurysm growth and rupture in the short‐term, but there is a lack of long‐term follow‐up studies. We aimed to determine whether unruptured intracranial aneurysms (UIAs) with AWE have a higher probability of aneurysm instability during long‐term follow‐up compared with those without AWE. Methods For
Laura T. van der Kamp +9 more
wiley +1 more source
The correlation between clinic and neuroimaging of cerebral small vessel disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Zheng⁃qi LU
doaj +1 more source
Annals of Neurology, EarlyView.Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao +4 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics
Annals of Neurology, EarlyView.Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino +23 more
wiley +1 more source
New Insight Into the Pathogenesis of Cerebral Small-Vessel Diseases.
Stroke, 2017 K. Müller +3 more
semanticscholar +1 more source
Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths
Annals of Neurology, EarlyView.Objective Though it is widely known that tau deposition affects brain structure, the precise localization of these effects is poorly understood, especially in relation to gyral and sulcal anatomy. We investigated whether tau pathology in Alzheimer's disease (AD) preferentially affects sulci, and particularly sulcal depths.
Samira A. Maboudian +10 more
wiley +1 more source