Results 291 to 300 of about 173,118 (376)

Salvianolic acid�B recovers cognitive deficits and angiogenesis in a cerebral small vessel disease rat model via the STAT3/VEGF signaling pathway

, 2017
Wei Wang, Wenli Hu
openalex   +2 more sources

Management of Calvarial Osteoradionecrosis After Treatment of Cutaneous Malignancy: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Osteoradionecrosis (ORN) is a recognized complication of radiotherapy. However, calvarial ORN (ORNC) following treatment for cutaneous malignancies is poorly understood. Shedding light on the limited evidence to date, this study aims to summarize existing evidence and highlight the research gaps.
Siyuan Pang, Elizabeth Concannon, Martin Higgins, Katharine Drummond, Peter Gearing, Maxim Devine, Albert Tiong, Anand Ramakrishnan, Carly Fox   +8 more
wiley   +1 more source

The risk factors and cognition disorders in different types of cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Zheng⁃qi LU
doaj   +1 more source

Clinical Outcome and Risk Factors for Progression of Prenatally Diagnosed Fetal Ventriculomegaly: A Retrospective Multicenter Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate the clinical outcome of fetuses with ventriculomegaly (VM), and to identify risk factors for progression of fetal VM in order to improve prenatal counseling. This was a multicenter, retrospective cohort study, comprising 229 cases with VM.
Anouk Moens, Zoe Albersnagel, Marieke B. Veenhof, Phebe N. Adama van Scheltema, Esther Sikkel, Mariëtte J. V. Hoffer, Brigitte H. W. Faas, Dineke Westra, Ilse Feenstra, Emilia K. Bijlsma, Gijs W. E. Santen, Corrie E. Erasmus, Cacha M. P. C. D. Peeters‐Scholte   +12 more
wiley   +1 more source

Trusting Your Gut When it Comes to the Origin of Parkinson's Disease

Movement Disorders, EarlyView.
Per Borghammer, Nathalie Van Den Berge, Casper Skjærbæk, Jacob Horsager   +3 more
wiley   +1 more source

Plasma Proteomic Profiling of a Group of Anxious Dogs by LC‐MS/MS: A Case–Control Study

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Purpose Anxiety is the most common underlying cause of behavioral problems in dogs, which remain a top reason for relinquishment and euthanasia. Despite its high prevalence, anxiety is often underdiagnosed, partly due to a limited understanding of biological processes and absence of diagnostic biomarkers.
Claudia Gaither, Robert Popp, Christoph H. Borchers, Francis Beaudry, Marion Desmarchelier   +4 more
wiley   +1 more source

White matter changes and gait decline in cerebral small vessel disease

, 2017
Helena M. van der Holst, Anil M. Tuladhar, Valerio Zerbi, Ingeborg W.M. van Uden, Karlijn F. de Laat, Esther M.C. van Leijsen, Mohsen Ghafoorian, Bram Platel, Mayra I. Bergkamp, Anouk G.W. van Norden, David G. Norris, Ewoud J. van Dijk, Amanda J. Kiliaan, F.‐E. de Leeuw   +13 more
openalex   +1 more source

Microglial Drivers of Alzheimer's Disease Pathology: An Evolution of Diverse Participating States

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Microglia, the resident immune‐competent cells of the brain, become dysfunctional in Alzheimer's disease (AD), and their aberrant immune responses contribute to the accumulation of pathological proteins and neuronal injury. Genetic studies implicate microglia in the development of AD, prompting interest in developing immunomodulatory therapies
Madison K. Kuhn, Elizabeth A. Proctor
wiley   +1 more source

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer\u27s disease [PDF]

, 2018
Bateman, Randall J, Benzinger, Tammie L. S., Buckles, Virginia, Cairns, Nigel J, et al.,, Fagan, Anne M, Holtzman, David M, Marcus, Daniel S, McDade, Eric, Morris, John C   +9 more
core   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source