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New Treatment Approaches to Modify the Course of Cerebral Small Vessel Diseases.

Stroke, 2019
See related articles, p 9, p 12, p 21, p 29, p 47 Cerebral small vessel diseases (cSVDs) are a common cause of stroke and an important contributor to age-related cognitive decline and risk for dementia. Yet there is surprisingly little information on how
Eric E. Smith, H. Markus
semanticscholar   +1 more source

Proteostasis in Cerebral Small Vessel Disease [PDF]

Frontiers in Neuroscience, 2019
Maintaining the homeostasis of proteins (proteostasis) by controlling their synthesis, folding and degradation is a central task of cells and tissues. The gradual decline of the capacity of the various proteostasis machineries, frequently in combination with their overload through mutated, aggregation-prone proteins, is increasingly recognized as an ...
openaire   +5 more sources

Update of Immunosenescence in Cerebral Small Vessel Disease [PDF]

Frontiers in Immunology, 2020
Aging of the central nervous system (CNS) is closely associated with chronic sterile low-grade inflammation in older organisms and related immune response. As an amplifier for neuro-inflammaging, immunosenescence remodels and deteriorates immune systems gradually with the passage of time, and finally contributes to severe outcomes like stroke, dementia
Banghao Jian, Mengyan Hu, Wei Cai, Wei Cai, Bingjun Zhang, Zhengqi Lu   +5 more
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Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study. [PDF]

, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Garcia, Melissa E, Gudnason, Vilmundur, Harris, Tamara B, Henry, Ronald M A, Jonsson, Palmi V, Launer, Lenore J, Levey, Andrew S, Mitchell, Gary F, Sigurdsson, Sigurdur, Stehouwer, Coen D A, van Buchem, Mark A, van Sloten, Thomas T   +11 more
core   +1 more source

Imaging scoring methods for cerebral small vessel disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
The pathogenesis of cerebral small vessel disease (CSVD) is not yet clear, and there is no effective treatment method at present. MRI is an important imaging in diagnosing.
PAN Xi⁃juan, XING Ying⁃qi, LIU Yu⁃mei   +2 more
doaj   +1 more source

Cerebral small vessel disease: Pathological mechanisms and potential therapeutic targets

Frontiers in Aging Neuroscience, 2022
Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular diseases primarily affecting small arteries, capillaries, arterioles and venules.
Yue Gao, Di Li, Jianwen Lin, Aline M. Thomas, Jianyu Miao, Dong Chen, Shen Li, Chengyan Chu   +7 more
semanticscholar   +1 more source

Genetics of Cerebral Small Vessel Disease [PDF]

Journal of Stroke, 2015
Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive impairment among the elderly and is a more frequent cause of stroke in Asia than in the US or Europe. Although traditional risk factors such as hypertension or diabetes mellitus are important in the development of cerebral SVD, the exact pathogenesis is still uncertain ...
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Dawson's Fingers in Cerebral Small Vessel Disease [PDF]

Frontiers in Neurology, 2020
To explore Dawson's fingers in cerebral small vessel disease (CSVD) and factors related to the development of Dawson's finger, we collected and analyzed clinical data of 65 patients with CSVD. We found a venous abnormality feature called Dawson's fingers around the ventricles in magnetic resonance images (MRIs) of 20 out of 65 patients with CSVD (30. 8%
Wenli Zhu, Zaiqiang Zhang, Ying Fu, Yaping Yan, Li Yang, Aowei Lv   +5 more
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Cerebral Venous Reflux and Dilated Basal Ganglia Perivascular Space in Hypertensive Intracerebral Hemorrhage [PDF]

Journal of Stroke, 2022
Background and Purpose Cerebral venous flow alterations potentially contribute to age-related white matter changes, but their role in small vessel disease has not been investigated. Methods This study included 297 patients with hypertensive intracerebral
Hsin-Hsi Tsai, Bo-Ching Lee, Ya-Fang Chen, Jiann-Shing Jeng, Li-Kai Tsai   +4 more
doaj   +1 more source

CADASIL Affects Multiple Aspects of Cerebral Small Vessel Function on 7T‐MRI

Annals of Neurology, 2022
Cerebral small vessel diseases (cSVDs) are a major cause of stroke and dementia. We used cutting‐edge 7T‐MRI techniques in patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), to establish ...
H. van den Brink, Anna Kopczak, T. Arts, L. Onkenhout, J. Siero, J. Zwanenburg, Sandra Hein, Mathias Hübner, B. Gesierich, M. Duering, M. Stringer, J. Hendrikse, J. Wardlaw, A. Joutel, M. Dichgans, G. Biessels   +15 more
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