Results 61 to 70 of about 212,620 (328)

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

open access: yes, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A.   +9 more
core   +1 more source

MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols

open access: yesAlzheimer's & Dementia, 2021
The MarkVCID consortium was formed under cooperative agreements with the National Institute of Neurologic Diseases and Stroke (NINDS) and National Institute on Aging (NIA) in 2016 with the goals of developing and validating biomarkers for the cerebral ...
Hanzhang Lu   +18 more
semanticscholar   +1 more source

Role of brain perfusion SPECT with 99mTc HMPAO in the assessment of response to drug therapy in patients with autoimmune vasculitis: a prospective study [PDF]

open access: yes, 2015
BACKGROUND: The diagnosis of vasculitis in the brain remains a quite difficult achievement. To the best of our knowledge, there is no imaging method reported in literature which is capable of reaching to a diagnosis of vasculitis with very high ...
Anna Margherita Maffione, 2   +11 more
core   +1 more source

Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]

open access: yes, 2020
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia   +7 more
core   +1 more source

MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols

open access: yesAlzheimer's & Dementia, 2021
The concept of vascular contributions to cognitive impairment and dementia (VCID) derives from more than two decades of research indicating that (1) most older individuals with cognitive impairment have post mortem evidence of multiple contributing ...
D. Wilcock   +30 more
semanticscholar   +1 more source

Stroke and migraine is there a possible comorbidity? [PDF]

open access: yes, 2016
The association between migraine and stroke is still a dilemma for neurologists. Migraine is associated with an increased stroke risk and it is considered an independent risk factor for ischaemic stroke in a particular subgroup of patients.
Del Balzo, Francesca   +7 more
core   +2 more sources

CADASIL Affects Multiple Aspects of Cerebral Small Vessel Function on 7T‐MRI

open access: yesAnnals of Neurology, 2022
Cerebral small vessel diseases (cSVDs) are a major cause of stroke and dementia. We used cutting‐edge 7T‐MRI techniques in patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), to establish ...
H. van den Brink   +15 more
semanticscholar   +1 more source

Age Related Changes in Cerebrovascular Reactivity and Its Relationship to Global Brain Structure [PDF]

open access: yes, 2015
ACKNOWLEDGMENTS This study was funded by Alzheimer’s Research UK (ARUK) and the Aberdeen Biomedical Imaging Centre, University of Aberdeen. GDW, ADM and CS are part of the SINASPE collaboration (Scottish Imaging Network - A Platform for Scientific ...
Ahearn, Trevor S.   +4 more
core   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

open access: yesNeural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Interaction between Alzheimer’s Disease and Cerebral Small Vessel Disease: A Review Focused on Neuroimaging Markers

open access: yesInternational Journal of Molecular Sciences, 2022
Alzheimer’s disease (AD) is characterized by the presence of β-amyloid (Aβ) and tau, and subcortical vascular cognitive impairment (SVCI) is characterized by cerebral small vessel disease (CSVD). They are the most common causes of cognitive impairment in
Si Eun Kim   +6 more
semanticscholar   +1 more source

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