Results 71 to 80 of about 173,118 (376)

Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke [PDF]

, 2014
Aims: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia.
Bailey, Emma L., Crawford, Wendy, Dominiczak, Anna F., Graham, Delyth, McBride, Martin W., McClure, John D., Smith, Colin, Sudlow, Cathie L.M., Wardlaw, Joanna M.   +8 more
core   +2 more sources

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]

, 2013
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
A Nitkunan, A Nitkunan, A Viswanathan, A Zhou, Andrew D. MacKinnon, Andrew J. Lawrence, AZ Burzynska, B Grassiot, B Patel, Bhavini Patel, C Cordonnier, C Junqué, CAM Wheeler-Kingshott, CM Fisher, DJ Werring, E Englund, EE Smith, EE Smith, F Fazekas, Hugh S. Markus, IA Awad, J Bamford, J Grimaud, JC van Swieten, Jean-Claude Baron, L Pantoni, M Duering, M Holtmannspötter, M Jenkinson, M Neeman, M O'Sullivan, M O'Sullivan, M O'Sullivan, N Shiee, Philip M. Rich, PJ Basser, PS Sachdev, R Della Nave, R Schmidt, RA Charlton, RA Charlton, Robin G. Morris, SK Song, SM Smith, SW Seo, Thomas R. Barrick, U Khan, Y Nagahama   +47 more
core   +11 more sources

Cardiovascular co-morbidities, inflammation and cerebral small vessel disease.

Cardiovascular Research, 2021
Cerebral small vessel disease (cSVD) is the most common cause of vascular cognitive impairment and affects all levels of the brain's vasculature. Features include diverse structural and functional changes affecting small arteries and capillaries that ...
Lowri E. Evans, Jade L Taylor, Craig J. Smith, Harry A T Pritchard, A. Greenstein, S. Allan   +5 more
semanticscholar   +1 more source

Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]

, 2001
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Aufenanger, Johannes, Bertsch, Thomas, Casarin, Wendy, Fassbender, Klaus, Höly, Sabine, Kuehl, Sandra, Mielke, Orell, Muehlhauser, Frank, Ragoschke, Andreas, Walter, Silke, Zimmer, Wilma   +10 more
core   +1 more source

Prevention and Management of Cerebral Small Vessel Disease [PDF]

Journal of Stroke, 2015
Lacunar infarcts/lacunes, white matter hyperintensities (WMH), and cerebral microbleeds (CMBs) are considered various manifestations of cerebral small vessel disease (SVD). Since the exact mechanisms of these manifestations differ, their associated risk factors differ.
Jong S. Kim, Vincent Mok
openaire   +3 more sources

A horse, a horse, my kingdom for a horse. Saddle thrombosis of carotid bifurcation in acute stroke [PDF]

, 2012
Background: Saddle thrombosis is less frequently detected in carotid arteries than in peripheral arterial embolism. The clot and the distal vessel patency have to be promptly recognized in these cases, because if the carotid vessel is open distally ...
DI PIERO, Vittorio, Edoardo Vicenzini, GIANNONI, Maria Fabrizia, LENZI, Gian Luigi, Maria Chiara Ricciardi, SIRIMARCO, GAIA, TOSCANO M.   +6 more
core   +1 more source

Targeting the brain’s glymphatic pathway: A novel therapeutic approach for cerebral small vessel disease

Neural Regeneration Research
Cerebral small vessel disease encompasses a group of neurological disorders characterized by injury to small blood vessels, often leading to stroke and dementia.
Yuhui Ma, Yan Han
doaj   +1 more source

Cerebral small vessel disease and Alzheimer’s disease

Clinical Interventions in Aging, 2015
Cerebral small vessel disease (CSVD) is a group of pathological processes with multifarious etiology and pathogenesis that are involved into the small arteries, arterioles, venules, and capillaries of the brain. CSVD mainly contains lacunar infarct or lacunar stroke, leukoaraiosis, Binswanger's disease, and cerebral microbleeds.
Liang-Jun Yan, Zhengang Tang, Zhiyou Cai, Hanjun Tu, Wenbo He, Chuanling Wang, Ming Xiao   +6 more
openaire   +5 more sources

Hypercholesterolemia induced cerebral small vessel disease

PLOS ONE, 2017
While hypercholesterolemia plays a causative role for the development of ischemic stroke in large vessels, its significance for cerebral small vessel disease (CSVD) remains unclear. We thus aimed to understand the detailed relationship between hypercholesterolemia and CSVD using the well described Ldlr-/- mouse model.We used Ldlr-/- mice (n = 16) and ...
Christoph Kleinschnitz, Solveig Jandke, Solveig Jandke, Stefanie Schreiber, Stefanie Schreiber, Hans-Jochen Heinze, Hans-Jochen Heinze, Daniela Urlaub, Peter Kraft, Alma Zernecke, Roxana O. Carare, Stine Mencl, Michael K. Schuhmann, Cornelia Garz   +13 more
openaire   +6 more sources

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter, Kessler, C., Krause, Klaus-Henning, Reuther, R.   +3 more
core   +1 more source