Results 11 to 20 of about 5,581,923 (161)

Mechanisms of Pericyte-Mediated Cancer Metastasis. [PDF]

Adv Sci (Weinh)
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Guo Z, Cao Y.
europepmc   +2 more sources

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study

Hepatology, EarlyView., 2022
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef, Milan J. Sonneveld, Maryam Kavousi, M. Arfan Ikram, Robert A. de Man, Robert J. de Knegt   +5 more
wiley   +1 more source

Preprint: Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease

, 2021
To understand the consequences of higher adiposity uncoupled from its adverse metabolic effects, we selected 37 diseases associated with obesity and genetic variants associated with different aspects of excess weight including metabolically “favourable ...
Lam Tsoi, Christopher Kabrhel, Philip E Stuart, Marc Gunter, Emma Vincent, Robin Beaumont, Philip Law, Caroline Bull, Hanieh Yaghootkar, Elizabeth Thomas, Timothy Frayling, Nikos Papadimitriou, Joshua Bell, Naveed Sattar, Jessica Tyrrell, Andrew Wood, Richard Houlston, Susan Martin, Jimmy Bell, Matthew Bown, James Elder   +20 more
core   +1 more source

Increased Cardiovascular Events and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients: 1 Year Prospective Single Centre Study. [PDF]

PLoS ONE, 2017
Several studies showed the close relationship between Rheumatoid Arthritis (RA) and cerebro-cardiovascular events (CVEs) and subclinical atherosclerosis.
Piero Ruscitti, Paola Cipriani, Francesco Masedu, Silvio Romano, Onorina Berardicurti, Vasiliki Liakouli, Francesco Carubbi, Paola Di Benedetto, Saverio Alvaro, Maria Penco, Marco Valenti, Roberto Giacomelli   +11 more
doaj   +1 more source

Burden of cardiovascular disease in a large contemporary cohort of patients with heterozygous familial hypercholesterolemia

Atherosclerosis Plus, 2022
Background and aims: Heterozygous familial hypercholesterolemia (HeFH) is increasingly better diagnosed and treatments can improve the cardiovascular prognosis.
Jean Ferrières, Michel Farnier, Eric Bruckert, Alexandre Vimont, Vincent Durlach, Emile Ferrari, Antonio Gallo, Franck Boccara, Dorota Ferrières, Sophie Béliard, Denis Angoulvant, Karine Aouchiche, Sophie Beliard, Franck Boccara, Eric Bruckert, Bertrand Cariou, Valérie Carreau, Alain Carrie, Sybil Charrieres, Yves Cottin, Mathilde Di Filippo, Caroline Dourmap, Pierre-Henri Ducluzeau, Vincent Durlach, Michel Farnier, Emile Ferrari, Dorota Ferrieres, Jean Ferrieres, Antonio Gallo, Regis Hankard, Jocelyn Inamo, Olga Kalmykova, Michel Krempf, Julie Lemale, Philippe Moulin, François Paillard, Noel Peretti, Agnes Perrin, Alain Pradignac, Yann Pucheu, Jean Pierre Rabes, Rachel Reynaud, Vincent Rigalleau, François Schiele, Ariane Sultan, Patrick Tounian, René Valero, Bruno Verges, Cecile Yelnik, Olivier Ziegler   +49 more
doaj   +1 more source

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Non-HIV chronic disease burden among transgender populations globally: A systematic review and narrative synthesis

Preventive Medicine Reports, 2020
Chronic disease is a growing concern for research, policy and clinical care. While the global burden of HIV for transgender populations has been comprehensively covered in recent systematic reviews, the same is not true for the burden of other chronic ...
Ashleigh J. Rich, Ayden I. Scheim, Mieke Koehoorn, Tonia Poteat   +3 more
doaj   +1 more source

PREDICTORS FOR DEVELOPMENT OF PERIPHERAL ARTERIAL DISEASE IN PANCREAS-KIDNEY TRANSPLANT PATIENTS AND IMPACT ON OUTCOMES

Angiologia e Cirurgia Vascular, 2021
Introduction: The risk of peripheral arterial disease (PAD) is significantly increased in patients with type 1 diabetes mellitus who have developed chronic kidney disease. Pancreas kidney transplantation seems to be a promising option for these patients
Beatriz Moreira, Daniel Mendes, La Salete Silva, Rui Almeida, Ivone Silva   +4 more
doaj   +1 more source

Is Socioeconomic Position Related to the Prevalence of Metabolic Syndrome? Influence of social class across the life course in a population-based study of older men [PDF]

, 2008
OBJECTIVE - To examine whether adult social class and childhood social class are related to metabolic syndrome in later life, independent of adult behavioral factors.RESEARCH DESIGN AND METHODS - This was a population-based cross-sectional study ...
Morris, R, Lennon, Lucy, Whincup, Peter H, Whincup, PH, Morris, Richard, Ramsay, SE, Lennon, L, Ramsay, Sheena E, Wannamethee, S G, Wannamethee, SG   +9 more
core   +1 more source

Age at menarche and its association with the metabolic syndrome and its components [PDF]

, 2011
The metabolic syndrome is a major public health challenge and identifies persons at risk for diabetes and cardiovascular disease. The aim of this study was to examine the association between age at menarche and the metabolic syndrome (IDF and NCEP ATP ...
Döring, Angela, Rathmann, Wolfgang, Meisinger, Christa, Stöckl, Doris, Peters, Annette, Kowall, Bernd, Thorand, Barbara, Huth, Cornelia, Heier, Margit, Stöckl, Heidi   +9 more
core   +1 more source