Corticotropin-releasing hormone as the homeostatic rheostat of feto-maternal symbiosis and developmental programming In utero and neonatal life [PDF]
A balanced interaction between the homeostatic mechanisms of mother and the devel- oping organism during pregnancy and in early neonatal life is essential in order to ensure optimal fetal development, ability to respond to various external and internal ...
Alcantara-Alonso +114 more
core +3 more sources
Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality [PDF]
BACKGROUND: Oxidative stress has been suggested to play a key role in the development of cardiovascular disease (CVD). The aim of our study was to investigate the associations of serum peroxiredoxin 4 (Prx4), a hydrogen peroxide-degrading peroxidase ...
Abbasi, A. +14 more
core +2 more sources
Effects of Ramadan fasting on cardiovascular risk factors: a prospective observational study
Background Previous research has shown that Ramadan fasting has beneficial effects on cardiovascular risk factors, however there are controversies. In the present study, the effect of Ramadan fasting on cardiovascular risk factors has been investigated ...
Nematy Mohsen +10 more
doaj +1 more source
Purpose: The goal of this study is to see if carotid strain and strain rate can predict major cardio-vascular events (MACE) in people who have metabolic syndrome (MS) over a 3-year period of time.
Sergiu Florin Arnăutu +3 more
doaj +1 more source
Achievement of multiple therapeutic targets for cardiovascular disease prevention. Retrospective analysis of real practice in Italy [PDF]
Background: Pharmacological therapy in patients at high cardiovascular (CV) risk should be tailored to achieve recommended therapeutic targets. Hypothesis: To evaluate individual global CV risk profile and to estimate the control rates of multiple ...
American Diabetes Association +33 more
core +1 more source
Cerebro-rhino orbital mucormycosis: An update
Summary: Mucormycosis is an uncommon fungal infection which can lead to fulminant necrotizing infection under optimal host condition. Fungi have the ability to invade blood vessels and can affect different parts of the body.
Upender Wali +2 more
doaj +1 more source
Correlation of Postprandial Hypertriglyceridemia with Carotid Intima Media Thickness in Patients with Type 2 Diabetes Mellitus [PDF]
Introduction: Macro vascular disease is a major cause of death in diabetic individuals. Because many diabetic individuals have multiple risk factors for atherosclerosis, the relative risks of Ischemic Heart Disease (IHD) and Cerebro-Vascular Disease (
Ashwani Kumar Sharma +3 more
doaj +1 more source
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]
Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent +2 more
core +1 more source
Humanin: a novel central regulator of peripheral insulin action. [PDF]
Decline in insulin action is a metabolic feature of aging and is involved in the development of age-related diseases including Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD).
Radhika H Muzumdar +12 more
doaj +1 more source
Irisin evokes bradycardia by activating cardiac-projecting neurons of nucleus ambiguus. [PDF]
Irisin is a newly identified hormone induced in muscle and adipose tissues by physical activity. This protein and its encoding gene have been identified in the brain; in addition, the precursor for irisin, FNDC5, can cross the blood-brain barrier.
Brailoiu, Eugen +3 more
core +2 more sources

