Results 31 to 40 of about 3,218 (94)

Liquid Chromatographic and Capillary Electromigration Techniques for the Analysis of Azole Antifungals

open access: yesJournal of Separation Science, Volume 48, Issue 4, April 2025.
ABSTRACT Since the introduction of azoles as antifungals in 1979, they gradually gained a spotlight in both medicinal and industrial fields. Other than being the leading antifungal medicinal drug agents, azoles have also been a major pesticide in agricultural industry.
Tuuliina Tuominen   +3 more
wiley   +1 more source

Evidence of Pellagra on 19th Century Human Crania From Northern Italy by Combining Stable Isotope and Paleopathological Analyses

open access: yesInternational Journal of Osteoarchaeology, Volume 35, Issue 2, March/April 2025.
ABSTRACT Pellagra is a disease caused by a nutritional deficiency, with fatal outcome due to multiple‐organ failure, that affected European rural areas until the early decades of the 20th century, especially Veneto region (Italy). At the skeletal level, previous studies pointed out that pathological signs left by the disease are generic and typical of ...
Nicola Carrara   +8 more
wiley   +1 more source

残余代谢危险因素与青年卒中 Residual Metabolic Risk Factors and Stroke in Young Adults

open access: yesZhongguo cuzhong zazhi
青年卒中一般指在18~50岁年龄段内发生的卒中,其发病率上升给我国带来了日益增加的社会经济负担。在探讨青年卒中的代谢危险因素时,除了传统的高血压、糖代谢异常、脂代谢异常和肥胖外,残余代谢危险因素亦不容忽视。本文重点关注了炎症、高同型半胱氨酸血症、高尿酸血症和肠道微生物群代谢产物这4种残余代谢危险因素对青年卒中的影响。炎症在青年卒中中的作用显著,与心源性脑栓塞这一重要病因的发生发展密切相关。高同型半胱氨酸血症通过影响血管内皮和凝血功能促进血栓形成,是有望预测卒中风险及预后的重要指标 ...
钱宇彤1,2,张书凡1,2,韩振翔3,吴维诚4,韩翔1,2 (QIAN Yutong1,2, ZHANG Shufan1,2, HAN Zhenxiang3, WU Weicheng4, HAN Xiang1,2 )
doaj   +1 more source

Neuropathological correlates of vulnerability and resilience in the cerebellum in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract INTRODUCTION We investigated whether the cerebellum develops neuropathology that correlates with well‐accepted Alzheimer's disease (AD) neuropathological markers and cognitive status. METHODS We studied cerebellar cytoarchitecture in a cohort (N = 30) of brain donors.
Colby L. Samstag   +15 more
wiley   +1 more source

Trichothiodystrophy due to ERCC2 Variants: Uncommon Contributor to Progressive Hypomyelinating Leukodystrophy

open access: yesMolecular Genetics &Genomic Medicine, Volume 13, Issue 2, February 2025.
This study reports a novel case of trichothiodystrophy (TTD) linked to compound heterozygous ERCC2 variants, presenting with progressive cerebral hypomyelination. The findings highlight a rare association between ERCC2 mutations and hypomyelinating leukodystrophy, expanding the current understanding of TTD‐related neurodevelopmental disorders. ABSTRACT
Ali Reza Tavasoli   +8 more
wiley   +1 more source

Preventive cytoprotection in social diseases

open access: yesТерапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov   +4 more
doaj  

Aterosclerosis y afectación de la función cognitiva Atherosclerosis and cognitive function impairment

open access: yesRevista Cubana de Investigaciones Biomédicas, 2012
La aterosclerosis es un proceso de origen multicausal y se acompaña de una gran variedad de manifestaciones clínicas y humorales. Son conocidos los factores de riesgo aterogénicos como dislipidemias, hipertensión arterial, diabetes mellitus, obesidad ...
Regino Piñeiro Lamas   +2 more
doaj  

DELIRIUM PERIOPERATORIO

open access: yesRevista Médica Clínica Las Condes, 2017
RESUMEN: Debido al cambio demográfico de las últimas décadas, los sistemas de salud se han visto enfrentados a atender a pacientes cada vez de mayor edad.El Delirium Perioperatorio (DPO) es la más seria y más frecuente complicación cognitiva del paciente
Jimena Rodríguez, Dra.
doaj  

Benefits of blackberry nectar (Rubus spp.) relative to hypercholesterolemia and lipid peroxidation Beneficios del néctar de mora (Rubus spp.) en relación con la hipercolesterolemia y la peroxidación lipídica

open access: yesNutrición Hospitalaria, 2011
Introduction: In humans, the normal metabolic activity produces free radicals that constantly, along with other risk factors, including hypercholesterolemia may be responsible for the onset of degenerative diseases.
P. R. Ferreira de Araujo   +5 more
doaj  

Tratamiento de la hipertensión arterial en el paciente con síndrome metabólico Hypertension treatment in patients with metabolic syndrome

open access: yesRevista Colombiana de Cardiología, 2010
El síndrome metabólico afecta alrededor de 25% a 45% de la población colombiana de acuerdo con los criterios diagnósticos propuestos por la Federación Internacional de Diabetes, los cuales, en nuestra población, aparecen como los más útiles. Bien se sabe
Patricio López-Jaramillo
doaj  

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