Klinefelter syndrome: cardiovascular abnormalities and metabolic disorders [PDF]
Klinefelter syndrome (KS) is one of the most common genetic causes of male infertility. This condition is associated with much comorbidity and with a lower life expectancy.
Calogero, A. E. +8 more
core +1 more source
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza +7 more
wiley +1 more source
Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry [PDF]
To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ...
Cannella, Roberto +6 more
core +1 more source
The Cerebellar Connectome Disruptions in Ischemic Stroke
Ischemic stroke disrupts the brain's modular organization (based on the Yeo/Buckner template). In patients with basal ganglia ischemic stroke, inter‐module functional connectivity is altered, characterized by increased intra‐cerebellar connectivity, reduced connectivity between ipsilesional cerebral and cerebellar modules, and enhanced connectivity ...
Xiuqin Wang +9 more
wiley +1 more source
Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]
Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb +14 more
core +1 more source
ABSTRACT The bidirectional interaction between sleep and epilepsy is well known. In particular, it has been established that sleep apnea can worsen epilepsy, whereas sleep apnea (SA) treatment has a beneficial effect on seizure control. However, the exact mechanisms whereby SA promotes epileptic seizures are unknown.
Christian M. Horvath +4 more
wiley +1 more source
Longitudinal effects of metabolic syndrome on Alzheimer and vascular related brain pathology. [PDF]
Background/aimsThis study examines the longitudinal effect of metabolic syndrome (MetS) on brain-aging indices among cognitively normal (CN) and amnestic mild cognitive impairment (aMCI) groups [single-domain aMCI (saMCI) and multiple-domain aMCI (maMCI)]
Alzheimer's Disease Neuroimaging Initiative +7 more
core +4 more sources
ApoE4 Homozygosity Is Associated With Increased Microglia Activation in Fatal COVID‐19
ABSTRACT Apolipoprotein E4 (APOE4) is recognized as a major risk factor for disorders such as Alzheimer's disease and may play a role in the dysregulation of microglia in various neurodegenerative conditions. APOE variants have also been proposed as potential risk factors for severe outcomes in COVID‐19.
Amar Hamdan +7 more
wiley +1 more source
Causes of brain dysfunction in acute coma: a cohort study of 1027 patients in the emergency department [PDF]
BACKGROUND: Coma of unknown etiology (CUE) is a major challenge in emergency medicine. CUE is caused by a wide variety of pathologies that require immediate and targeted treatment.
Braun, Mischa +5 more
core +1 more source
Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley +1 more source

