Normal and Dysregulated Sphingolipid Metabolism: Contributions to Podocyte Injury and Beyond
CellsPodocyte health is vital for maintaining proper glomerular filtration in the kidney. Interdigitating foot processes from podocytes form slit diaphragms which regulate the filtration of molecules through size and charge selectivity. The abundance of lipid
Matthew Tolerico +2 more
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A Novel Oligosaccharide on Bovine Peripheral Myelin Glycoprotein P0 [PDF]
, 2003 Sulfated oligosaccharides have found in glycoproteins in myelin in the PNS, such as P0 and PASII/PMP22. These glycoproteins are involved in the interaction of cell membranes and play important roles in the formation and maintenance of myelin sheaths ...
北村 邦男, 野村 正彦, 閻 剣虹
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P-selectin mediates metastatic progression through binding to sulfatides on tumor cells [PDF]
, 2017 Hematogenous carcinoma metastasis is associated with tumor cell emboli formation, which is now known to be facilitated by selectins. P-selectin-mediated interactions of platelets with cancer cells are based mostly on mucin- and glycosaminoglycan-type ...
Borsig, L., Callewaert, N., Garcia, J.
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Phase behavior of selected artificial lipids [PDF]
, 2016 The flexibility of biomembranes is based on the physical-chemical properties of their main components - glycerophospholipids. The structure of these modular amphiphilic molecules can be modified through organic synthesis making it possible to study ...
Brezesinski, Gerald +2 more
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Structure of Cerebrosides. II. Small Angle X-Ray Diffraction Study of Cerasine [PDF]
, 1979 R. Hosemann +4 more
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Canine distemper, a re-emerging morbillivirus with complex neuropathogenic mechanisms [PDF]
, 2017 Paramyxoviruses are responsible for a wide variety of diseases both in humans and in animals. Common to many paramyxoviruses is the fact that they can cause neurological symptoms in their final host.
Griot, Christian +3 more
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Enzymic synthesis of cerebroside from ceramide and uridine diphosphate galactose [PDF]
, 1969 Yozo Fujino, Masahiro Nakano
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Reduced plasma hexosylceramides in frontotemporal dementia are a biomarker of white matter integrity
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION Blood biomarkers are needed to facilitate new therapeutic trials and improve management of behavioral variant frontotemporal dementia (bvFTD).
Oana C. Marian +8 more
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Constituents of Euphorbiaceae, 13. Comm. [1] Isolation and Structure Elucidation of Five Cerebrosides from Euphorbia characias L [PDF]
, 1994 Gioacchino Falsone +5 more
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Discover ChemistryDespite advances in ACTs, drug-resistant Plasmodium falciparum strains necessitates new therapeutics. While neem’s broad-spectrum bioactivity is well-known, our recent identification of host-plant synergies prompted this focused investigation into neem’s
Garba Dauda +10 more
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