Results 1 to 10 of about 2,226 (116)

Therapeutic Potential of Sea Cucumber-Derived Bioactives in the Prevention and Management of Brain-Related Disorders: A Comprehensive Review [PDF]

Marine Drugs
The popularity of bioactive compounds extracted from sea cucumbers is growing due to their wide application in the pharmaceutical industry, particularly in the development of drugs for neurological disorders.
Purnima Rani Debi, Hrishika Barua, Mirja Kaizer Ahmmed, Shuva Bhowmik   +3 more
doaj   +2 more sources

New Ceramides and Cerebrosides from the Deep-Sea Far Eastern Starfish Ceramaster patagonicus [PDF]

Marine Drugs, 2022
Three new ceramides (1–3) and three new cerebrosides (4, 8, and 9), along with three previously known cerebrosides (ophidiocerebrosides C (5), D (6), and CE-3-2 (7)), were isolated from a deep-sea starfish species, the orange cookie starfish Ceramaster ...
Timofey V. Malyarenko, Viktor M. Zakharenko, Alla A. Kicha, Alexandra S. Kuzmich, Olesya S. Malyarenko, Anatoly I. Kalinovsky, Roman S. Popov, Vasily I. Svetashev, Natalia V. Ivanchina   +8 more
doaj   +2 more sources

Forward-predictive SERS-based chemical taxonomy for untargeted structural elucidation of epimeric cerebrosides [PDF]

Nature Communications
Achieving untargeted chemical identification, isomeric differentiation, and quantification is critical to most scientific and technological problems but remains challenging. Here, we demonstrate an integrated SERS-based chemical taxonomy machine learning
Emily Xi Tan, Shi Xuan Leong, Wei An Liew, In Yee Phang, Jie Ying Ng, Nguan Soon Tan, Yie Hou Lee, Xing Yi Ling   +7 more
doaj   +2 more sources

Two Cerebrosides Isolated from the Seeds of Sterculia lychnophora and Their Neuroprotective Effect

Molecules, 2013
Two cerebrosides named 1-O-b-D-glucopyranosyl-(2S,3R,4E,8Z)-2-[(2-hydroxyoctadecanoyl)amido]-4,8-octadecadiene-1,3-diol (1) and soya-cerebroside I (2) were isolated from the seeds of Sterculia lychnophora for the first time.
Ru-Feng Wang, Xiu-Wen Wu, Di Geng
exaly   +3 more sources

Cerebrosides of human aorta: isolation, identification of the hexose, and fatty acid distribution

Journal of Lipid Research, 1968
Cerebrosides have been isolated from adult human aortic tissue. Each aorta was divided into portions classified as normal, fatty streaks, fibrous plaques, or complicated lesions.
J. Lindsley Foote, Eric Coles
doaj   +1 more source

Characterization of trimethylsilyl derivatives of cerebrosides by direct inlet-chemical ionization mass spectrometry.

Journal of Lipid Research, 1978
Submicrogram quantities of trimethylsilyl derivatives of cerebrosides obtained from the spleen of a patient with Gaucher's disease and from bovine brain were analyzed by direct probe inlet-chemical ionization mass spectrometry, using isobutane as the ...
T Murata, T Ariga, M Oshima, T Miyatake
doaj   +1 more source

A method for fractionation of cerebrosides into classes with different fatty acid compositions

Journal of Lipid Research, 1972
A method is described for the separation of beef brain cerebrosides into three fractions containing different classes of fatty acids: nonhydroxy (I), unsaturated nonhydroxy (II), and hydroxy fatty acid cerebrosides (III).
Aureliu J. Acher, Julian N. Kanfer
doaj   +1 more source

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by β-xylosidase and transxylosidase reactions

Journal of Lipid Research, 2021
: Deficiency of glucocerebrosidase (GBA), a lysosomal β-glucosidase, causes Gaucher disease. The enzyme hydrolyzes β-glucosidic substrates and transglucosylates cholesterol to cholesterol-β-glucoside.
Daphne E. Boer, Mina Mirzaian, Maria J. Ferraz, Kimberley C. Zwiers, Merel V. Baks, Marc D. Hazeu, Roelof Ottenhoff, André R.A. Marques, Rianne Meijer, Jonathan C.P. Roos, Timothy M. Cox, Rolf G. Boot, Navraj Pannu, Herman S. Overkleeft, Marta Artola, Johannes M. Aerts   +15 more
doaj   +1 more source

Determination of less than a nanomol of cerebrosides by high performance liquid chromatography with gradient elution analysis

Journal of Lipid Research, 1977
A gradient elution high performance liquid chromatography method with detection at 230 nm for the analysis of perbenzoylated cerebrosides containing hydroxy and nonhydroxy fatty acids is described.
F B Jungalwala, L Hayes, R H McCluer
doaj   +1 more source

Effect of cerebroside preparations on sterol excretion in the rat*

Journal of Lipid Research, 1960
The addition of cerebroside preparations to synthetic diets fed to rats caused an increased excretion of sterol in the feces as measured by the Liebermann-Burchard reaction.
K.K. Carroll
doaj   +1 more source