Results 21 to 30 of about 2,777 (213)

Cerebrosides

, 2016

core   +2 more sources

Galactokinase 1 is the source of elevated galactose-1-phosphate and cerebrosides are modestly reduced in a mouse model of classic galactosemia. [PDF]

JIMD Rep
Classic galactosemia (CG) arises from loss‐of‐function mutations in the Galt gene, which codes for the enzyme galactose‐1‐phosphate uridylyltransferase (GALT), a central component in galactose metabolism.
Mangini L, Lawrence R, Lopez ME, Graham TC, Bauer CR, Nguyen H, Su C, Ramphal J, Crawford BE, Hartl TA.   +9 more
europepmc   +2 more sources

Quantitative analysis of brain galactosylceramides by high performance liquid chromatography of their perbenzoyl derivatives

Journal of Lipid Research, 1976
A high performance liquid chromatographic (HPLC) method for analysis of galactosylceramides as their benzoyl derivatives has been devised. Samples containing 10-150 nmoles of monohexosylceramides are benzoylated by heating for 60 min at 60 ° C in 0.5 ml ...
E H McCluer, J E Evans
doaj   +1 more source

Concentration and fatty acid composition of cerebrosides and sulfatides in mature and immature human brain

Journal of Lipid Research, 1966
The fatty acid composition of cerebrosides and sulfatides from frontal lobe gray and white matter was determined for five fresh and four formalinized adult brains and for eight infants.
John H. Menkes, Michel Philippart, Maria Carla Concone   +2 more
doaj   +1 more source

Sphingolipids of Asteroidea and Holothuroidea: Structures and Biological Activities

Marine Drugs, 2021
Sphingolipids are complex lipids widespread in nature as structural components of biomembranes. Commonly, the sphingolipids of marine organisms differ from those of terrestrial animals and plants.
Timofey V. Malyarenko, Alla A. Kicha, Valentin A. Stonik, Natalia V. Ivanchina   +3 more
doaj   +1 more source

Structure and properties of totally synthetic galacto- and gluco-cerebrosides

Journal of Lipid Research, 1999
The structural and thermal properties of aqueous dispersions of the totally synthetic cerebrosides, d-erythro-N-palmitoyl galactosyl- and glucosyl-C18-sphingosine (C16:0-GalCer and C16:0-GluCer, respectively) have been studied using differential scanning
Kumkum Saxena, Richard I. Duclos, Peter Zimmermann, Richard R. Schmidt, G. Graham Shipley   +4 more
doaj   +1 more source

Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells

Metabolites, 2020
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of ...
Peeranat Jatooratthawichot, Chutima Talabnin, Lukana Ngiwsara, Yepy Hardi Rustam, Jisnuson Svasti, Gavin E. Reid, James R. Ketudat Cairns   +6 more
doaj   +1 more source

Lonijaposides, novel cerebrosides from Lonicera japonica.

, 2006
Six novel cerebrosides, lonijaposides A1–A4, B1 and B2 (1–6) have been isolated from the flowers of Lonicera japonica. Their structures were established on the basis of 1D, 2D (DEPT, HMQC, HMBC and COSY) NMR, ESI-QTOF-MS/MS and chemical ...
Kumar, Neeraj, Singh , Bikram, Gupta , A P, Kaul , V K   +3 more
core   +2 more sources

Biosynthesis of the cerebroside odd-numbered fatty acids*

Journal of Lipid Research, 1962
Rats were injected with radioactive acetate or propionate and, after four days, the saturated fatty acids were isolated from the brains and the brain cerebrosides.
Amiya K. Hajra, Norman S. Radin
doaj   +1 more source

Structural Analysis of Oxidized Cerebrosides from the Extract of Deep-Sea Sponge Aulosaccus sp.: Occurrence of Amide-Linked Allylically Oxygenated Fatty Acids

Molecules, 2020
The structural elucidation of primary and secondary peroxidation products, formed from complex lipids, is a challenge in lipid analysis. In the present study, rare minor oxidized cerebrosides, isolated from the extract of a far eastern deep-sea glass ...
Elena A. Santalova, Vladimir A. Denisenko, Pavel S. Dmitrenok   +2 more
doaj   +1 more source