Results 11 to 20 of about 2,161 (179)

Erythroside: A New Cerebroside and Other Compounds From Erythrina Caffra Thunb. (Fabaceae) Stem Bark, With Cytotoxicity and Antioxidant Evaluation. [PDF]

Chem Biodivers
ABSTRACT The chemical investigation of a CH2Cl2:MeOH (1:1) extract of the stem bark of Erythrina caffra resulted in the isolation and characterisation of the novel cerebroside, erythroside (1), alongside eight other known compounds (2‐9). The isolated compounds were characterized by FT‐IR, 1D and 2D NMR spectroscopy, and ESI‐MS analysis.
Tsakem B, Serem JC, Hlophe YN, Kamdem Kengne MH, Sandjo LP, Ndinteh DT, Teponno RB, Ambele MA, Siwe Noundou X.   +8 more
europepmc   +2 more sources

Characterization of trimethylsilyl derivatives of cerebrosides by direct inlet-chemical ionization mass spectrometry.

Journal of Lipid Research, 1978
Submicrogram quantities of trimethylsilyl derivatives of cerebrosides obtained from the spleen of a patient with Gaucher's disease and from bovine brain were analyzed by direct probe inlet-chemical ionization mass spectrometry, using isobutane as the ...
T Murata, T Ariga, M Oshima, T Miyatake
doaj   +1 more source

A method for fractionation of cerebrosides into classes with different fatty acid compositions

Journal of Lipid Research, 1972
A method is described for the separation of beef brain cerebrosides into three fractions containing different classes of fatty acids: nonhydroxy (I), unsaturated nonhydroxy (II), and hydroxy fatty acid cerebrosides (III).
Aureliu J. Acher, Julian N. Kanfer
doaj   +1 more source

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by β-xylosidase and transxylosidase reactions

Journal of Lipid Research, 2021
: Deficiency of glucocerebrosidase (GBA), a lysosomal β-glucosidase, causes Gaucher disease. The enzyme hydrolyzes β-glucosidic substrates and transglucosylates cholesterol to cholesterol-β-glucoside.
Daphne E. Boer, Mina Mirzaian, Maria J. Ferraz, Kimberley C. Zwiers, Merel V. Baks, Marc D. Hazeu, Roelof Ottenhoff, André R.A. Marques, Rianne Meijer, Jonathan C.P. Roos, Timothy M. Cox, Rolf G. Boot, Navraj Pannu, Herman S. Overkleeft, Marta Artola, Johannes M. Aerts   +15 more
doaj   +1 more source

Determination of less than a nanomol of cerebrosides by high performance liquid chromatography with gradient elution analysis

Journal of Lipid Research, 1977
A gradient elution high performance liquid chromatography method with detection at 230 nm for the analysis of perbenzoylated cerebrosides containing hydroxy and nonhydroxy fatty acids is described.
F B Jungalwala, L Hayes, R H McCluer
doaj   +1 more source

Effect of cerebroside preparations on sterol excretion in the rat*

Journal of Lipid Research, 1960
The addition of cerebroside preparations to synthetic diets fed to rats caused an increased excretion of sterol in the feces as measured by the Liebermann-Burchard reaction.
K.K. Carroll
doaj   +1 more source

Quantitative analysis of brain galactosylceramides by high performance liquid chromatography of their perbenzoyl derivatives

Journal of Lipid Research, 1976
A high performance liquid chromatographic (HPLC) method for analysis of galactosylceramides as their benzoyl derivatives has been devised. Samples containing 10-150 nmoles of monohexosylceramides are benzoylated by heating for 60 min at 60 ° C in 0.5 ml ...
E H McCluer, J E Evans
doaj   +1 more source

Concentration and fatty acid composition of cerebrosides and sulfatides in mature and immature human brain

Journal of Lipid Research, 1966
The fatty acid composition of cerebrosides and sulfatides from frontal lobe gray and white matter was determined for five fresh and four formalinized adult brains and for eight infants.
John H. Menkes, Michel Philippart, Maria Carla Concone   +2 more
doaj   +1 more source

Structure and properties of totally synthetic galacto- and gluco-cerebrosides

Journal of Lipid Research, 1999
The structural and thermal properties of aqueous dispersions of the totally synthetic cerebrosides, d-erythro-N-palmitoyl galactosyl- and glucosyl-C18-sphingosine (C16:0-GalCer and C16:0-GluCer, respectively) have been studied using differential scanning
Kumkum Saxena, Richard I. Duclos, Peter Zimmermann, Richard R. Schmidt, G. Graham Shipley   +4 more
doaj   +1 more source

Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells

Metabolites, 2020
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of ...
Peeranat Jatooratthawichot, Chutima Talabnin, Lukana Ngiwsara, Yepy Hardi Rustam, Jisnuson Svasti, Gavin E. Reid, James R. Ketudat Cairns   +6 more
doaj   +1 more source