Effect of oral ligustrazine phosphate with cerebroside carnosine on neurological function and serum inflammatory factors among patients with ischemic cerebrovascular disease: a quasi-experimental study. [PDF]
Zhao Q, Liu Z.
europepmc +3 more sources
Alternate pathways of cerebroside catabolism [PDF]
AbstractA search was made for new degradative pathways for glucosyl and galactosyl ceramides in an effort to explain the failure of these lipids to accumulate in the brains of children with Krabbe's or Gaucher's disease. Using various buffers and incubation conditions, we tested brain homogenates from 12 day old rats with the stearateālabeled and ...
Yuh-Nan Lin, Norman S. Radin
openalex +4 more sources
Isotopic studies of the biosynthesis of the cerebroside fatty acids in rats
Groups of weanling rats were given a single injection of labeled acetate and were sacrificed at intervals up to 56 days. The saturated acids of brain cerebrosides and brain were isolated by gas-liquid chromatography, counted, and chemically degraded to ...
Amiya K. Hajra, Norman S. Radin
doaj +2 more sources
Phytoconstituents of Withania somnifera (L.) Dunal (Ashwagandha) unveiled potential cerebroside sulfotransferase inhibitors: insight through virtual screening, molecular dynamics, toxicity, and reverse pharmacophore analysis. [PDF]
Singh N, Singh AK.
europepmc +2 more sources
Exploration of phytoconstituents of Medhya Rasayana herbs to identify potential inhibitors for cerebroside sulfotransferase through high-throughput screening. [PDF]
Singh N, Singh AK.
europepmc +2 more sources
<i>Lannea coromandelica</i> (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity. [PDF]
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Siam NH +10 more
europepmc +2 more sources
Therapeutics Potential of Cronassial in Experimental Autoimmune Encephalomyelitis: Insights Into Glycosphingolipids and Humoral Immunity. [PDF]
Currently, significant attention is being paid to the study of the mechanisms underlying the development of multiple sclerosis (MS), especially factors related to humoral immunity, apoptosis, and sphingolipid metabolism processes. These factors play a key role in neuroinflammation and neurodegeneration during both the acute and chronic stages of the ...
Ghazaryan G +3 more
europepmc +2 more sources
Properties of cerebroside galactosidase [PDF]
SUMMARY Rat brain cerebrosidase was shown by centrifugal fractionation to be a lysosomal enzyme. The pH optimum was found to be 4.5. Taurocholate greatly stimulated its action. The addition of palmitic acid had little effect on the enzyme activity, but ceramide, sphingosine, and ceramide lactoside inhibited.
Bowen, David M., Radin, Norman S.
openaire +3 more sources
Sphingomyelin, ceramide, cerebroside, and cerebroside sulfate from beef brain were isolated by column chromatography in quantitative yield and in pure form. The fatty acid composition of each sphingolipid was determined by gas-liquid chromatography (GLC).
John S. O'Brien, George Rouser
doaj +1 more source
Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]
Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Barrie, Jennifer A. +8 more
core +1 more source

