Results 31 to 40 of about 8,895 (244)

New Cytotoxic Natural Products from the Red Sea Sponge Stylissa carteri

Marine Drugs, 2020
Bioactivity-guided isolation supported by LC-HRESIMS metabolic profiling led to the isolation of two new compounds, a ceramide, stylissamide A (1), and a cerebroside, stylissoside A (2), from the methanol extract of the Red Sea sponge Stylissa carteri ...
Reda F. A. Abdelhameed, Eman S. Habib, Nermeen A. Eltahawy, Hashim A. Hassanean, Amany K. Ibrahim, Anber F. Mohammed, Shaimaa Fayez, Alaa M. Hayallah, Koji Yamada, Fathy A. Behery, Mohammad M. Al-Sanea, Sami I. Alzarea, Gerhard Bringmann, Safwat A. Ahmed, Usama Ramadan Abdelmohsen   +14 more
doaj   +1 more source

Marine Fungal Cerebroside Flavuside B Protects HaCaT Keratinocytes against Staphylococcus aureus Induced Damage

Marine Drugs, 2021
Cerebrosides are glycosylated sphingolipids, and in mammals they contribute to the pro-/anti-inflammatory properties and innate antimicrobial activity of the skin and mucosal surfaces.
Ekaterina A. Chingizova, Ekaterina S. Menchinskaya, Artur R. Chingizov, Evgeny A. Pislyagin, Elena V. Girich, Anton N. Yurchenko, Irina V. Guzhova, Valery V. Mikhailov, Dmitry L. Aminin, Ekaterina A. Yurchenko   +9 more
doaj   +1 more source

Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics

Journal of Lipid Research, 2005
By using shotgun lipidomics based on the separation of lipid classes in the electrospray ion source (intrasource separation) and two-dimensional (2D) MS techniques (Han, X., and R. W. Gross. 2004.
Xianlin Han, Hua Cheng
doaj   +1 more source

Antileishmanial and Antiplasmodial Activities of Secondary Metabolites from the Root of Antrocaryon klaineanum Pierre (Anacardiaceae)

Molecules, 2023
Antrocaryon klaineanum is traditionally used for the treatment of back pain, malaria, female sterility, chlamydiae infections, liver diseases, wounds, and hemorrhoid.
Gabrielle Ange Amang à Ngnoung, Lazare S. Sidjui, Peron B. Leutcha, Yves O. Nganso Ditchou, Lauve R. Y. Tchokouaha, Gaëtan Herbette, Beatrice Baghdikian, Theodora K. Kowa, Desire Soh, Raoul Kemzeu, Madan Poka, Patrick H. Demana, Xavier Siwe Noundou, Alembert T. Tchinda, Fabrice Fekam Boyom, Alain M. Lannang, Barthélemy Nyassé   +16 more
doaj   +1 more source

Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori [PDF]

, 2017
published_or_final_versio
Chai, Z, CHANG, YY, Chu, IK, Hu, L, Lai, YT, Li, H, QUAN, Q, Sun, H, Wang, JJ, WANG, Y, Xia, W, Xu, F, Yang, X, YANG, Y   +13 more
core   +1 more source

Cerebrosides and Steroids from the Edible Mushroom Meripilus giganteus with Antioxidant Potential

Molecules, 2020
The detailed chemical analysis of the methanol extract of Meripilus giganteus (Pers.) P. Karst. led to the isolation of two new cerebrosides, mericeramides A (1) and B (2) together with cerebroside B (3), ergosterol (4), 3β-hydroxyergosta-7,22-diene
András Sárközy, Zoltán Béni, Miklós Dékány, Zoltán Péter Zomborszki, Kinga Rudolf, Viktor Papp, Judit Hohmann, Attila Ványolós   +7 more
doaj   +1 more source

Detection and toxicity evaluation of pyrrolizidine alkaloids in medicinal plants Gynura bicolor and Gynura divaricata collected from different Chinese locations [PDF]

, 2017
Two edible plants in Southeast Asia, Gynura bicolor and G.divaricata, are not only known to be nutritive but also useful as medicinal herbs. Previous phytochemical investigation of Gynura species showed the presence of hepatotoxic pyrrolizidine alkaloids
Chen, Jian, De Kimpe, Norbert, Fang, Lian-Xiang, Li, Wei-Lin, Lu, Han, Mangelinckx, Sven, Verschaeve, Luc, Wang, Zheng-Tao   +7 more
core   +2 more sources

Characteristic distribution of glycolipids in gadoid fish nerve tissues and its bearing on phylogeny.

Journal of Lipid Research, 1992
Glycolipids were isolated from nerve tissues of gadoid fishes including Alaskan pollack and Pacific cod. Their chemical structures were determined by gas-liquid chromatography and gas chromatography-mass spectrometry, and their constituents were analyzed
Y Tamai, H Kojima, S Saito, K Takayama-Abe, H Horichi   +4 more
doaj   +1 more source

Synthesis of chiral α-hydroxy acids via palladium-catalyzed C(sp^3)–H alkylation of lactic acid [PDF]

, 2016
Herein we report a Pd-catalyzed alkylation of lactic acid with the assistance of 8-aminoquinoline auxiliary. A wide range of alkyl iodides bearing β-hydrogen atoms are compatible with the reaction conditions, providing a practical and straightforward ...
Chen, Kai, Li, Xin, Shi, Bing-Feng, Zhang, Shuo-Qing   +3 more
core   +2 more sources

TREM2 sustains microglial expansion during aging and response to demyelination [PDF]

, 2015
Microglia contribute to development, homeostasis, and immunity of the CNS. Like other tissue-resident macrophage populations, microglia express the surface receptor triggering receptor expressed on myeloid cells 2 (TREM2), which binds polyanions, such as
Colonna, Marco, Fontana, Elena, Gilfillan, Susan, Poliani, Pietro Luigi, Robinette, Michelle L, Wang, Yaming, Yamanishi, Yoshinori   +6 more
core   +1 more source