Results 41 to 50 of about 5,647 (249)

Fragment C of Tetanus Toxin : New Insights into Its Neuronal Signaling Pathway [PDF]

open access: yes, 2012
When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
Acheson   +95 more
core   +3 more sources

Characterization of myelin of chick sciatic nerve during development

open access: yesJournal of Lipid Research, 1976
Myelin was isolated from the sciatic nerves of chicks of ages 18-day embryonic, 1-day, 4-day, 7-day post-hatch, and adult to study developmental changes in lipid composition of this structure.
M R Oulton, C Mezei
doaj   +1 more source

Methods for treating bone deficit conditions with benzothiazole [PDF]

open access: yes, 1999
" Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or ""linker"" defined as including a covalent bond per se so as to space the aromatic systems at a distance 1.5-15 .ANG., are effective in ...
Baindur, Nand   +6 more
core   +1 more source

Effect of Expression of Human Glucosylceramidase 2 Isoforms on Lipid Profiles in COS-7 Cells

open access: yesMetabolites, 2020
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of ...
Peeranat Jatooratthawichot   +6 more
doaj   +1 more source

Structural Analysis of Oxidized Cerebrosides from the Extract of Deep-Sea Sponge Aulosaccus sp.: Occurrence of Amide-Linked Allylically Oxygenated Fatty Acids

open access: yesMolecules, 2020
The structural elucidation of primary and secondary peroxidation products, formed from complex lipids, is a challenge in lipid analysis. In the present study, rare minor oxidized cerebrosides, isolated from the extract of a far eastern deep-sea glass ...
Elena A. Santalova   +2 more
doaj   +1 more source

AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing

open access: yesAdvanced Intelligent Discovery, EarlyView.
AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley   +1 more source

Correlation between metabolomic profile constituents and feline pancreatic lipase immunoreactivity

open access: yesJournal of Veterinary Internal Medicine, 2022
Background Feline pancreatic lipase immunoreactivity (fPLI) is commonly used to diagnose pancreatitis in cats (FP). Untargeted metabolomics has been extensively applied in human and veterinary medicine, but no metabolomic studies regarding FP have been ...
Magdalena Maria Krasztel   +5 more
doaj   +1 more source

Analysis of glycolipids in vegetable lecithin with HPLC-ELSD [PDF]

open access: yes, 2014
Vegetable lecithins play an important role in the microstructural and macroscopic properties of food and cosmetic products. They are widely used as a natural emulsifier.
De Vrieze, Mike   +5 more
core   +1 more source

Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis [PDF]

open access: yes, 2003
We have previously shown that patients with primary progressive multiple sclerosis (MS) have significantly elevated plasma levels of antibody to GM3 ganglioside compared to patients with relapsing-remitting MS, healthy subjects and patients with other ...
Acarin   +38 more
core   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

open access: yesNano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri   +2 more
wiley   +1 more source

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