Results 51 to 60 of about 2,542 (211)

Changes in sphingosine and fatty acid components of the gangliosides in developing rat and human brain

open access: yesJournal of Lipid Research, 1966
Rat brain increases in weight after birth in three stages: (I) rapidly for the first 2 weeks, (II) at a lower rate from 2 to 5 weeks, and (III) at a still lower rate from 5 weeks to 5 months.
Abraham Rosenberg, Nora Stern
doaj   +1 more source

Cerebrosides and 2-Pyridone Alkaloids from the Halotolerant Fungus Penicillium chrysogenum Grown in a Hypersaline Medium

open access: yes, 2016
Five new cerebrosides, chrysogesides A−E (1−5), and two new 2-pyridone alkaloids, chrysogedones A and B (6 and 7), were isolated from the fermentation broth of Penicillium chrysogenum PXP-55, a halotolerant fungus grown in a hypersaline medium.
Peipei Liu (339689)   +5 more
core   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

open access: yesNano Select, Volume 7, Issue 2, February 2026.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri   +2 more
wiley   +1 more source

Characterization of myelin of chick sciatic nerve during development

open access: yesJournal of Lipid Research, 1976
Myelin was isolated from the sciatic nerves of chicks of ages 18-day embryonic, 1-day, 4-day, 7-day post-hatch, and adult to study developmental changes in lipid composition of this structure.
M R Oulton, C Mezei
doaj   +1 more source

Sphingolipids in Emotional Well‐Being

open access: yesJournal of Neurochemistry, Volume 170, Issue 2, February 2026.
Sphingolipids are essential constituents of neuronal membranes and are increasingly recognized as contributors to the key behavioral manifestations associated with emotional well‐being. ABSTRACT Emotional well‐being is a multifactorial concept, which comprises not only life quality of human individuals, but also their mental and physical health.
L. S. Kalinichenko   +4 more
wiley   +1 more source

Colloidal Graphite-Assisted Laser Desorption/Ionization Mass Spectrometry and MSn of Small Molecules. 1. Imaging of Cerebrosides Directly from Rat Brain Tissue

open access: yes, 2016
Graphite-assisted laser desorption/ionization (GALDI) mass spectrometry (MS) was investigated for analysis of cerebrosides in a complex total brain lipid extract.
Edward S. Yeung (1615138)   +1 more
core   +1 more source

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam   +10 more
wiley   +1 more source

Correlation between metabolomic profile constituents and feline pancreatic lipase immunoreactivity

open access: yesJournal of Veterinary Internal Medicine, 2022
Background Feline pancreatic lipase immunoreactivity (fPLI) is commonly used to diagnose pancreatitis in cats (FP). Untargeted metabolomics has been extensively applied in human and veterinary medicine, but no metabolomic studies regarding FP have been ...
Magdalena Maria Krasztel   +5 more
doaj   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Decoding the Sphingolipid Landscape of Clear Cell Renal Cell Carcinoma: A Single‐Cell‐Guided Prognostic Model Built With 101 Machine Learning

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Background Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of kidney cancer and shows marked heterogeneity in progression, metastasis, and therapeutic response. Sphingolipid metabolism has emerged as an important regulator of tumor progression and the tumor microenvironment, but its cell‐state‐specific role in ccRCC ...
Jinbang Huang   +10 more
wiley   +1 more source

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