Results 71 to 80 of about 5,647 (249)

The Role of Pomegranate (Punica granatum) in Cancer Prevention and Treatment: Modulating Signaling Pathways From Inflammation to Metastasis

open access: yesFood Science &Nutrition, Volume 13, Issue 2, February 2025.
Punica granatum (pomegranate) exhibits significant anti‐cancer properties due to its polyphenol‐rich extracts, which modulate signaling pathways involved in inflammation, angiogenesis, and tumor progression. Review highlights its potential to prevent and treat various cancers, including prostate, breast, lung, and colon cancers, by leveraging its ...
Abdur Rauf   +11 more
wiley   +1 more source

Lipid class analysis of the central nervous system of myelin-deficient Wistar rats.

open access: yesJournal of Lipid Research, 1982
Brains and spinal cords of myelin-deficient (md) and littermate control rats were analyzed serially for myelin lipids during the period from 13 to 32 days of age. The glycolipids of md rat brains were severely reduced and remained so during the period of
C K Csiza
doaj   +1 more source

Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds [PDF]

open access: yes, 2018
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen.
Domínguez Pérez, Pilar Esther   +3 more
core   +2 more sources

Nutritional, Nutraceutical, and Medicinal Potential of Cantharellus cibarius Fr.: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 13, Issue 1, January 2025.
This review explores the nutritional, nutraceutical, and medicinal potential of Cantharellus cibarius, known as the “Golden chanterelle.” Emphasizing its rich composition of bioactive compounds and wide range of health benefits, the review also covers ecological significance, preservation strategies, and potential applications in dietary supplements ...
Ajay Kumar   +9 more
wiley   +1 more source

A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]

open access: yes, 2017
There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C.   +11 more
core   +2 more sources

Pogostemon cablin Acts as a Key Regulator of NF‐κB Signaling and Has a Potent Therapeutic Effect on Intestinal Mucosal Inflammation

open access: yesMediators of Inflammation, Volume 2025, Issue 1, 2025.
Persistent intestinal inflammation is a major contributor to various diseases, including digestive disorders, immune dysregulation, and cancer. The NF‐κB signaling pathway is pivotal in the inflammatory response of intestinal cells, regulating the secretion of inflammatory factors, mediating signal transduction, and activating receptors. In colitis, NF‐
Yuqing Deng   +8 more
wiley   +1 more source

The Antitumor Constituents from Hedyotis Diffusa Willd

open access: yesMolecules, 2017
As a TCM, Hedyotis diffusa Willd. has been using to treat malignant tumors, and many studies also showed that the extracts from Hedyotis diffusa Willd. possessed evident antitumor activities.
Changfu Wang   +7 more
doaj   +1 more source

Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics [PDF]

open access: yes, 2012
Heat shock protein 90 (Hsp90) is a promising cancer drug target as a molecular chaperone critical for stabilization and activation of several of the oncoproteins that drive cancer progression.
Millson, S. H., Piper, P. W.
core   +1 more source

6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols

open access: yesJournal of Lipid Research
Gaucher disease (GD) is a lysosomal storage disorder (LSD) resulting from inherited glucocerebrosidase (GBA1) deficiency. GD diagnosis relies on GBA1 activity assays, typically employing 4-methylumbelliferyl-β-D-glucopyranoside (4MU-β-Glc) as fluorogenic
Stef Bannink   +10 more
doaj   +1 more source

Quantitative analysis of plasma neutral glycosphingolipids by high performance liquid chromatography of their perbenzoyl derivatives

open access: yesJournal of Lipid Research, 1977
A quantitative high performance liquid chromatography method for the analysis of neutral glycosylceramides as their perbenzoyl derivatives has been devised.
M D Ullman, R H McCluer
doaj   +1 more source

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