Results 91 to 100 of about 2,777 (213)

Fatty acid composition of brain glycolipids in Alzheimer's disease, senile dementia, and cerebrocortical atrophy

Journal of Lipid Research, 1968
Quantitative fatty acid compositions are reported for human cerebral gray matter glycolipids (gangliosides, cerebrosides, and cerebroside sulfates) in Alzheimer's disease (presenile dementia) and related disorders of the central nervous system.
George D. Cherayil
doaj   +1 more source

6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols

Journal of Lipid Research
Gaucher disease (GD) is a lysosomal storage disorder (LSD) resulting from inherited glucocerebrosidase (GBA1) deficiency. GD diagnosis relies on GBA1 activity assays, typically employing 4-methylumbelliferyl-β-D-glucopyranoside (4MU-β-Glc) as fluorogenic
Stef Bannink, Kateryna O. Bila, Joosje van Weperen, Nina A.M. Ligthart, Maria J. Ferraz, Rolf G. Boot, Daan van der Vliet, Daphne.E.C. Boer, Herman S. Overkleeft, Marta Artola, Johannes M.F.G. Aerts   +10 more
doaj   +1 more source

The structural and functional role of myelin fast-migrating cerebrosides: pathological importance in multiple sclerosis

, 2011
A family of neutral glycosphingolipids containing a 3-O-acetyl-sphingosine galactosylceramide (3-SAG) has been characterized. Seven new derivatives of galactosylceramide (GalCer), designated as fast-migrating cerebrosides (FMCs) by TLC retention factor ...
Maria Podbielska, Edward L Hogan, Levery, Steven B, Steven B Levery, Podbielska, Maria, Hogan, Edward L   +5 more
core   +1 more source

GLYCOSYLTRANSFERASES OF RAT BRAIN THAT MAKE CEREBROSIDES: SUBSTRATE SPECIFICITY, INHIBITORS, AND ABNORMAL PRODUCTS 1 [PDF]

, 1976
Brain homogenates from young rats were assayed for their ability to synthesize cerebrosides from radioactive UDP-galactose or UDP-glucose and ceramide. A comparison of galactose transfer with ceramides made from different 2-hydroxy acids showed that the ...
Warren, K. R., Misra, R. S., Radin, Norman S., Arora, Ramesh C.   +3 more
core   +1 more source

Palmitoylation of STREX domain confers cerebroside sensitivity to the BKCa channel [PDF]

, 2014
Our previous study reported that cerebrosides from traditional Chinese medicine Baifuzi directly interact with the STREX domain of BKCa channels, which in turn results in the therapeutic effect of Baifuzi on ischemic stroke.
Zhou, Li, Qi, Jianhua, Wang, Mingyan, Zhang, Yujiao, Qi, Zhi, Zou, Jun   +5 more
core   +1 more source

Separation of phosphatidyl ethanolamine, phosphatidyl serine, and other phospholipids by thin-layer chromatography*

Journal of Lipid Research, 1962
Thin-layer chromatography of phospholipids and cerebrosides was performed on Silica Gel G plates using a mixture of chloroform-methanol-acetic acid-water as development solvent.
Vladimir P. Skipski, Robert F. Peterson, Marion Barclay   +2 more
doaj   +1 more source

Establishment of erythro configuration of ceramides from beef brain and chicken liver

Journal of Lipid Research, 1965
The sphingosine moiety of ceramides isolated from beef brain and chicken liver has been characterized as having the erythro stereochemical configuration.
Vernell Groom, Michael Sribney
doaj   +1 more source

Cerebrosides alter the lyotropic and thermotropic phase transitions of DOPE:DOPC and DOPE:DOPC:sterol mixtures [PDF]

, 1997
Freezing injury in rye and oat is a consequence of the formation of the inverted hexagonal (HII) phase in regions where the plasma membrane is brought into close proximity with cytoplasmic membranes during freeze-induced dehydration.
Steponkus, Peter L, Webb, Murray S, Thomas C Irving, Murray S Webb, Peter L Steponkus, Irving, Thomas C   +5 more
core   +1 more source

Confirmation of minor components of less polar neutral and acidic glycolipids in monkey brain tissue

Journal of Lipid Research, 2001
Crude glycolipids, prepared without alkali treatment in advance, were separated into neutral and acidic glycolipids by DEAE-Sephadex A-25 (acetate form) column chromatography.
Tamotsu Taketomi, Eiko Sugiyama, Kei-ichi Uemura, Atsushi Hara, Hiroya Hidaka, Minoru Tozuka, Tetsuo Nakabayashi, Tsutomu Katsuyama   +7 more
doaj   +1 more source

Turnover of the fatty acids of rat brain gangliosides, glycerophosphatides, cerebrosides, and sulfatides as a function of age

Journal of Lipid Research, 1965
Rats of three different ages (7, 13, and 22 days) were given a single injection of acetate-1-14C, then sacrificed at intervals (4 hr, 2 days, 10 days, and 30 days).
Yasuo Kishimoto, W. Ewart Davies, Norman S. Radin   +2 more
doaj   +1 more source