Results 101 to 110 of about 44,109 (276)

Cerebrospinal fluid physiology: visualization of cerebrospinal fluid dynamics using the magnetic resonance imaging Time-Spatial Inversion Pulse method

open access: yes, 2014
Previously there have been no methods for directly tracing the flow of cerebrospinal fluid (CSF) under physiological conditions, and the circulation of CSF has therefore been studied and visualized by injecting a radioactively labeled tracer or ...
Shinya Yamada, Yamada, Shinya
core   +1 more source

Label‐Free Detection of a Neurotransmitter Using an Aptamer‐Functionalized Amorphous IGZO Transistor

open access: yesAdvanced Materials Interfaces, EarlyView.
An aptamer‐functionalized amorphous IGZO thin‐film transistor enables label‐free electrical detection of the neurotransmitter serotonin under liquid‐gated operation. Stepwise surface functionalization ensures stable biomolecule integration and efficient electrostatic coupling.
Ngoc Thanh Ho   +3 more
wiley   +1 more source

Mathematical modelling and analysis of cerebrospinal mechanics: an investigation into the parthogenesis of syringomyelia [PDF]

open access: yes
Syringomyelia is a disease in which fluid-filled cavities, called syrinxes, form in the spinal cord causing progressive loss of sensory and motor functions.
Elliott, Novak Samuel Jon
core  

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Cerebrospinal fluid dynamics in the field of neurosurgery.

open access: yesThe Bulletin of Tokyo Medical and Dental University, 1979
Alteration in the cerebrospinal fluid (CSF) circulation was studied in 62 patients with neurosurgical diseases by CT cisternography using a water-soluble contrast medium, metrizamide, and also with radionuclide (169Yb- or 111In-DTPA) cisternography. As a rule, the patterns of both methods were in good agreement.
openaire   +2 more sources

Dynamics of brain-derived proteins in cerebrospinal fluid [PDF]

open access: yesClinica Chimica Acta, 2001
The recent theory of blood-cerebrospinal fluid (CSF) barrier function and dysfunction connects molecular flux and CSF flow rate. A reduced CSF flow rate is sufficient to account for the observed hyperbolic relation between different blood-derived protein concentrations in CSF in cases of a blood-CSF barrier dysfunction.The dynamics of brain-derived ...
openaire   +3 more sources

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Are Generalized Reduced Cerebrospinal Fluid Dynamics and Optic Nerve Sheath Compartmentation Sequential Steps in the Pathogenesis of Normal-Tension Glaucoma? [Response to Letter]

open access: yesEye and Brain, 2021
Hanspeter E Killer,1 Achmed Pircher2,3 1Department of Biomedicine, University Hospital Basel & University Basel, Basel, Switzerland; 2Department of Neuroscience/Ophthalmology, Uppsala University, Uppsala, Sweden; 3Department of Ophthalmology ...
Killer HE, Pircher A
doaj  

Flow Analysis of Cerebrospinal Fluid inside Catheters used for Hydrocephalus Patients According to Brain MRI Image by Means of CFD [PDF]

open access: yesChemical Process Design
(1) The treatment of hydrocephalus is the use of cerebrospinal shunts. These shunts are made up of different parts. One of the most important parts of these shunts is their catheter, which is placed inside the ventricle of the brain in order to drain ...
Saeed Moghadam Deymeh
doaj   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

open access: yesAdvanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis   +32 more
wiley   +1 more source

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