Results 41 to 50 of about 1,400,457 (288)

Dual-energy CT cisternography in the evaluation of CSF leaks: A novel approach

Radiology Case Reports, 2018
Cerebrospinal fluid leaks pose a serious threat to patients as they represent an unchecked communication between the subarachnoid space and the extracranial environment. Accurate localization of the leakage site is essential for treatment planning.
Alexandra M. Foust, DO, Xuan V. Nguyen, MD, PhD, Luciano Prevedello, MD, MPH, Eric C. Bourekas, MD, MBA, FACR, Daniel J. Boulter, MD   +4 more
doaj   +1 more source

Evaluation of endoscopic repair of cerebrospinal fluid rhinorrhea

Interdisciplinary Neurosurgery, 2021
Introduction: Cerebrospinal fluid (CSF) rhinorrhoea is a leakage of CSF fluid from the subarachnoid space through the frontal, sphenoidal or ethmoidal sinuses to the nose.
Mohamed Mahmoud Okasha, Ahmed Aly Ibrahim, Henry Schroeder, Mohamed El-Rahmani, Ayman El-Medani, Osama Saad Abdelaziz, Zaki Seddik Yehia   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

A Computationally Efficient Hybrid Leakage Model for Modeling Leakage in Positive Displacement Compressors [PDF]

, 2012
An empirical frictional correction factor to the isentropic nozzle model has been developed for application to leakage modeling in scroll, rotary and other similar compressors. This correction factor is derived by calculating the leakage mass flow with a
Groll, Eckhard A., Braun, James E., Horton, W. Travis, Bell, Ian H.   +3 more
core   +1 more source

Unintentional injection of contrast agent into the subdural space during an epidural blood patch procedure identified the site of cerebrospinal fluid leak: a case report

JA Clinical Reports
Background CT myelography is a definitive diagnostic tool for cerebrospinal fluid leakage. We report a case in which the site of a cerebrospinal fluid leak that had been difficult to identify on CT myelography was fortuitously localized owing to ...
Momoko Hattori, Hiroai Okutani, Mayuu Kobata, Daisuke Ishimoto, Yumiko Takao, Nobutaka Kariya, Munetaka Hirose   +6 more
doaj   +1 more source

Traumatic pneumorrhachis associated with cerebral fluid leakage evaluated with magnetic resonance myelography

Clinical Case Reports, 2023
Attention should be paid to cerebrospinal fluid leakage in patients with pneumorrhachis associated with vertebral body trauma. If pneumorrhachis is detected, further imaging investigation and bed rest should be considered as appropriate.
Kazuki Sugaya, Ken Iseki
doaj   +1 more source

Why human color vision cannot reliably detect cerebrospinal fluid xanthochromia [PDF]

, 2005
Background - Visual assessment of cerebrospinal fluid (CSF) for xanthochromia ( yellow color) is practiced by the majority of laboratories worldwide as a means of diagnosing intracranical bleeds.Methods - Colorimetric and spectrophotometric analysis of ...
Sharpe, TL, Keir, G, Petzold, A
core  

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source