Results 51 to 60 of about 1,400,457 (288)

Management of spontaneous cerebrospinal fluid leakage: A surgical case series

Interdisciplinary Neurosurgery, 2022
Background: The pathophysiology and optimal management of spontaneous cerebrospinal fluid (CSF) leakage is poorly understood. Here, we present a case series of 36 patients who underwent surgical management of spinal CSF leakage with discussion of ...
Amrou Abdelrahman, Joshua C. Bizilis, Scott Davies, Arul Bala   +3 more
doaj   +1 more source

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L., Niedmann, P., Poser, S., Otto, M., Kretzschmar, Hans A., Otto, Markus, Poser, Sigrid, Schmidt, H., Schroter, A., Kretzschmar, H. A.   +9 more
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Giant Subgaleal cerebrospinal fluid leakage: An unusual complication of chronic subdural hematoma surgery [PDF]

, 2017
We report a rare case of chronic subdural hematoma complicated with a Giant subgaleal cerebrospinal fluid leakage. Physical examination was performed with no alteration in mental status and no focal neurological disorder.
Alvis-Miranda, Hernando Raphael, Calderon-Miranda, Willem, Pacheco-Hernandez, Alfonso, Agrawal, Amit, Moscote-Salazar, Luis Rafael   +4 more
core   +2 more sources

The use of Hadad Flap to Decrease the Prevalence and Risk of Cerebrospinal Fluid Leak and Improve Outcome after Trans-Sphenoidal Pituitary Adenectomy 

Advanced Medical Journal
Background and objectives: In the majority of pituitary adenectomy surgeries, postoperative cerebrospinal fluid leaking is a challenge. Clinical professionals must prioritize the identification of particular risk factors and the resolution of this ...
Ranj Aso Mohammed Saeed Saeed, Ari Sami Hussain Nadhim Nadhim   +1 more
doaj   +1 more source

From Rigid to Soft Robotic Approaches for Neuroendoscopy

Advanced Robotics Research, EarlyView.
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday, Irena Zubak, Andreas Raabe, Josie Hughes   +3 more
wiley   +1 more source

A practical and economical method for frontal sinus reconstruction after frontal craniotomy: A single-center experience with 140 patients

Frontiers in Surgery, 2022
BackgroundFrontal sinus exposure is a common consequence of frontal craniotomy. Cerebrospinal fluid leakage and infection are the major postoperative complications that may occur as a result of the open frontal sinus.
Youwei Guo, Xianyong Fu, Wen Yin, Zhipeng Jiang, Yirui Kuang, Zhaoping Wu, Yudong Cao, Jun Tan, Jun Tan, Xing-jun Jiang, Xing-jun Jiang   +10 more
doaj   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Incidence and Risk Factors for Symptomatic Spinal Epidural Hematoma Following Posterior Thoracic Spinal Surgery in a Single Institute

Global Spine Journal, 2022
Study Design: Case-control study. Objectives: To investigate the incidence of symptomatic spinal epidural hematoma (SSEH) and recognize its risk factors in a cohort of patients undergoing posterior thoracic surgery in isolation.
Longjie Wang MD, Hui Wang MD, Zhuoran Sun MD, Zhongqiang Chen MD, Chuiguo Sun, Weishi Li MD   +5 more
doaj   +1 more source