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The Relationship Between Human Cerebrospinal Fluid Proteins and the Risk of Delirium: A Study Based on Genetic Data [PDF]

open access: yesBrain and Behavior
Background Delirium is an acute cognitive disturbance that is linked to increased healthcare costs, extended hospitalization, and a greater incidence of adverse outcomes, including cognitive decline.
Zhihui Xu   +6 more
doaj   +2 more sources

Alterations in cerebrospinal fluid proteins in a presymptomatic primary glioma model. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Understanding the early relationship between brain tumor cells and their environment could lead to more sensitive biomarkers and new therapeutic strategies. We have been using a rodent model of neurocarcinogenesis in which all animals develop
John C Whitin   +7 more
doaj   +2 more sources

Discovery of cerebrospinal fluid biomarkers for different dementias using mass spectrometry‐based proteomics [PDF]

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
INTRODUCTION Common forms of dementia include Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD). Disease specific biomarkers are needed for differential disease diagnosis.
Marijke E. Stokkel   +13 more
doaj   +2 more sources

Proteomic-based evidence for adult neurogenesis in birds and mammals as indicated from cerebrospinal fluid

open access: yesNeural Regeneration Research, 2022
Adult neurogenesis is the life-long process of neural stem cell proliferation, differentiation into neurons, migration, and incorporation into the existing neuronal circuits.
Eleni Voukali, Michal Vinkler
doaj   +1 more source

Altered offspring neurodevelopment in an L-NAME-induced preeclampsia rat model

open access: yesFrontiers in Pediatrics, 2023
IntroductionTo investigate the mechanism underlying the increased risk of subsequent neurodevelopmental disorders in children born to mothers with preeclampsia, we evaluated the neurodevelopment of offspring of a preeclampsia rat model induced by the ...
Noriyuki Nakamura   +18 more
doaj   +1 more source

The detection of surfactant proteins A, B, C and D in the human brain and their regulation in cerebral infarction, autoimmune conditions and infections of the CNS. [PDF]

open access: yesPLoS ONE, 2013
Surfactant proteins (SP) have been studied intensively in the respiratory system. Surfactant protein A and surfactant protein D are proteins belonging to the family of collectins each playing a major role in the innate immune system.
Stefan Schob   +7 more
doaj   +1 more source

Estimation of cerebrospinal fluid protein [PDF]

open access: yesJournal of Clinical Pathology, 1968
Three turbidometric methods and one method using ultraviolet spectrophotometry for estimating total cerebrospinal fluid protein have been examined. The necessity for preliminary dialysis renders the ultraviolet method unsuitable for routine use. The turbidometric method of Meulemans (1960) using a sulphosalicylic acid-sodium sulphate ...
C A, Pennock, L P, Passant, F G, Bolton
openaire   +2 more sources

Exploration of the mechanism by which icariin modulates hippocampal neurogenesis in a rat model of depression

open access: yesNeural Regeneration Research, 2022
Icariin (ICA) has a significant capacity to protect against depression and hippocampal injury, but it cannot effectively cross the blood-brain barrier and accumulate in the brain.
Ning-Xi Zeng   +7 more
doaj   +1 more source

Different Metabolomic and Proteomic Profiles of Cerebrospinal Fluid in Ventricular and Lumbar Compartments in Relation to Leptomeningeal Metastases

open access: yesMetabolites, 2022
The different molecular profiles of cerebrospinal fluid (CSF) between ventricular and lumbar compartments remain elusive, especially in the context of leptomeningeal metastasis (LM), which affects CSF flow.
Ji-Woong Kwon   +9 more
doaj   +1 more source

SCO-spondin, a giant matricellular protein that regulates cerebrospinal fluid activity

open access: yesFluids and Barriers of the CNS, 2021
Cerebrospinal fluid is a clear fluid that occupies the ventricular and subarachnoid spaces within and around the brain and spinal cord. Cerebrospinal fluid is a dynamic signaling milieu that transports nutrients, waste materials and neuroactive ...
Vania Sepúlveda   +4 more
doaj   +1 more source

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