Results 21 to 30 of about 113,579 (302)

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease. [PDF]

open access: yesPLoS ONE, 2016
Alzheimer's disease is a neurodegenerative disorder accounting for more than 50% of cases of dementia. Diagnosis of Alzheimer's disease relies on cognitive tests and analysis of amyloid beta, protein tau, and hyperphosphorylated tau in cerebrospinal ...
Payam Emami Khoonsari   +10 more
doaj   +1 more source

Cerebrospinal Fluid Protein Concentrations in Hydrocephalus

open access: yesChildren, 2023
CSF protein levels are altered in neurological disorders, such as hydrocephalus of different etiologies. In this retrospective observational study, we analyzed cerebrospinal fluid (CSF) samples in hydrocephalic diseases such as aqueductal stenosis (AQS, n = 27), normal pressure hydrocephalus (NPH, n = 24), hydrocephalus communicans (commHC, n = 25) and
Florian Wilhelmy   +8 more
openaire   +3 more sources

Protein variability in cerebrospinal fluid and its possible implications for neurological protein biomarker research.

open access: yesPLoS ONE, 2018
Cerebrospinal fluid is investigated in biomarker studies for various neurological disorders of the central nervous system due to its proximity to the brain. Currently, only a limited number of biomarkers have been validated in independent studies.
Lukas M Schilde   +10 more
doaj   +1 more source

What Can N-glycomics and N-glycoproteomics of Cerebrospinal Fluid Tell Us about Alzheimer Disease?

open access: yesBiomolecules, 2021
Proteomics—large-scale studies of proteins—has over the last decade gained an enormous interest for studies aimed at revealing proteins and pathways involved in disease.
Stefan Gaunitz   +2 more
doaj   +1 more source

Cisternal versus lumbar cerebrospinal fluid lactate concentration in healthy dogs

open access: yesVeterinární Medicína, 2020
The analysis of cerebrospinal fluid biomarkers provides a wide range of information about the neurological health of a patient. Lactate is a metabolic precursor necessary for brain gluconeogenesis.
Alba Galan   +6 more
doaj   +1 more source

Cerebrospinal Fluid Protein Changes in Preeclampsia [PDF]

open access: yesHypertension, 2018
The molecular mechanisms underlying seizure susceptibility in preeclampsia are unknown. We hypothesized that altered expression of distinct proteins in the cerebrospinal fluid (CSF) may reflect pathophysiological changes in the central nervous system that contribute to the neurological manifestations of severe preeclampsia. We obtained CSF
Erin, Ciampa   +7 more
openaire   +2 more sources

One-time intrathecal triamcinolone acetonide application alters the redox potential in cerebrospinal fluid of progressive multiple sclerosis patients: a pilot study

open access: yesTherapeutic Advances in Neurological Disorders, 2016
Introduction: Cerebrospinal fluid analysis may provide insight into the interplay between chronic inflammation and response to treatment. Objectives: To demonstrate the impact of one intrathecal triamcinolone injection on the redox potential and on ...
Thomas Müller   +5 more
doaj   +1 more source

Neuroimmunological findings of Angiostrongylus cantonensis meningitis in ecuadorian patients

open access: yesArquivos de Neuro-Psiquiatria, 2011
Meningitis caused by Angiostrongylus cantonensis has recently been reported in patients resulting from the first outbreaks in subtropical regions of Ecuador. METHOD: Eight young adult patients from the two outbreaks were studied.
Alberto J. Dorta-Contreras   +6 more
doaj   +1 more source

Kinetics-like equation for cerebrospinal fluid-blood diffusion models

open access: yesRevista Cubana de Investigaciones Biomédicas, 2020
Introduction: The diffusion of proteins from the blood to the cerebrospinal fluid is influenced by its molecular weight and by the intrinsic properties and biological properties of the protein. Objective: Determinate the diffusion of new proteins as they
José Alejandro Rodríguez-Pérez   +6 more
doaj  

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid

open access: yesJournal of Parkinson’s Disease, 2016
Background: Clinical diagnosis of parkinsonian syndromes like Parkinson’s disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Andrea Boman   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy