Results 281 to 290 of about 101,605 (316)

The Construction of ceRNA Regulatory Network Unraveled Prognostic Biomarkers and Repositioned Drug Candidates for the Management of Pancreatic Ductal Adenocarcinoma. [PDF]

Curr Issues Mol Biol
Aydin B, Okutan K, Aydogan OO, Sinha R, Turanli B.   +4 more
europepmc   +1 more source

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ceRNA in cancer: possible functions and clinical implications

Journal of Medical Genetics, 2015
Competing endogenous RNAs (ceRNAs) are transcripts that can regulate each other at post-transcription level by competing for shared miRNAs. CeRNA networks link the function of protein-coding mRNAs with that of non-coding RNAs such as microRNA, long non-coding RNA, pseudogenic RNA and circular RNA.
Xiaolong Qi, Nan Wu
exaly   +5 more sources

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Cell, 2011
Leonardo Salmena, Laura Poliseno, Yvonne Tay   +2 more
exaly   +2 more sources

LncRNA-MIAT promotes thyroid cancer progression and function as ceRNA to target EZH2 by sponging miR-150-5p

Cell Death and Disease, 2021
While long noncoding RNAs (lncRNAs) have been reported to play an important role in human cancer types, they remain poorly understood in papillary thyroid carcinoma (PTC).
Tuanqi Sun, Zhuoying Wang
exaly   +2 more sources

circRNA-002178 act as a ceRNA to promote PDL1/PD1 expression in lung adenocarcinoma

Cell Death and Disease, 2020
Circular RNAs (circRNAs) have been identified play a vital role in various different types of cancer via sponging miRNAs (microRNAs). However, their role in lung adenocarcinoma (LUAD) remains largely unclear.
JunFeng Wang, Xuhai Zhao, Yanbo Wang, Fenghai Ren, Dawei Sun, Yubo Yan, Xianglong Kong, Jianlong Bu, Mengfeng Liu, Shidong Xu   +9 more
exaly   +2 more sources

Identification of hub lncRNA ceRNAs in multiple sclerosis based on ceRNA mechanisms

Molecular Genetics and Genomics, 2021
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system, and the pathogenesis is influenced by genetic susceptibility. Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) play essential roles in complex diseases, including acting as competing endogenous RNAs (ceRNAs).
Yanjun Ding, Taotao Li, Xinwei Yan, Mintian Cui, Chao Wang, Situo Wang, Fengmin Zhang, Ruijie Zhang   +7 more
openaire   +3 more sources

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

Molecular Cancer, 2017
Several of the thousands of human long noncoding RNAs (lncRNAs) have been functionally characterized, yet their potential involvement in hepatocellular carcinoma (HCC) remains poorly understood.
Haojie Jin, Cun Wang, Jing-Yuan Fang
exaly   +2 more sources

The role of a ceRNA regulatory network based on lncRNA MALAT1 site in cancer progression

Biomedicine and Pharmacotherapy, 2021
Hao Liu
exaly   +2 more sources

An Overview of the Computational Models Dealing with the Regulatory ceRNA Mechanism and ceRNA Deregulation in Cancer

2021
Pools of RNA molecules can act as competing endogenous RNAs (ceRNAs) and indirectly alter their expression levels by competitively binding shared microRNAs. This ceRNA cross talk yields an additional posttranscriptional regulatory layer, which plays key roles in both physiological and pathological processes.
Federica Conte, Giulia Fiscon, Pasquale Sibilio, Pasquale Sibilio, Paola Paci, Paola Paci, Valerio Licursi   +6 more
openaire   +4 more sources