Assessment of the diagnostic value of serum ceruloplasmin for Wilson’s disease in children
Background Serum ceruloplasmin is one of the major diagnostic parameters for Wilson’s disease (WD). Age and gender difference of serum ceruloplasmin remain controversy.
Xinshuo Lu +12 more
doaj +1 more source
Role of serum ceruloplasmin in the diagnosis of Wilson's disease: A large Chinese study
BackgroundConventionally, serum ceruloplasmin levels below the lower reference limit (0. 20 g/L) is considered a diagnostic cutoff point for Wilson's disease (WD).
Yue Yang +9 more
doaj +1 more source
DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN [PDF]
BACKGROUND: Copper deficiency has been linked to alterations in lipid metabolism and hepatic steatosis. Oxidative stress plays a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD).
Vinicius S NUNES +5 more
doaj +1 more source
Study of serum ceruloplasmin and zinc in type 2 diabetes mellitus
Background and objective: Ceruloplasmin is the major copper-carrying protein in the blood and plays a role in iron metabolism. Zinc is an essential trace element for human health, which activates about 200 enzymes.
Amanj Zrar Hasan +2 more
doaj +1 more source
Ceruloplasmin is considered the main copper transport protein which is proposed to have a role in cancer. Ceruloplasmin is an acute phase reactant and antioxidant enzyme, has been found to be increased in sera of patients with several types of cancers ...
Shahlaa Shafiq Rozoqi
doaj +1 more source
Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus [PDF]
BackgroundOxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress.
Min Jung Lee +6 more
doaj +1 more source
Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley +1 more source
Host-Imposed Copper Poisoning Impacts Fungal Micronutrient Acquisition during Systemic Candida albicans Infections [PDF]
This work was supported by the European Research Council (http://erc.europa.eu/: STRIFE Advanced Grant ERC-2009-AdG-249793). A.J.P.B. was also supported by the UK Biotechnology and Biological Research Council (www.bbsrc.ac.uk: Research Grants BB/F00513X ...
Ballou, Elizabeth R. +7 more
core +7 more sources
Transcriptional regulation of copper metabolism genes in the liver of fetal and neonatal control and iron-deficient rats [PDF]
Acknowledgments The authors’ work is supported by Scottish Government (Rural and Environmental Scientific and Analytical Services). We are grateful to Ms Val Stevens for analytical and technical assistance and to the Biological Resource Facility staff ...
Hayes, Helen +3 more
core +2 more sources
Myeloperoxidase is a key factor promoting development of halogenative/oxidative stress under inflammatory conditions. Previously, we have discovered complexes including myeloperoxidase and its physiological inhibitor, ceruloplasmin in blood plasma of ...
A. V. Sokolov +6 more
doaj +1 more source

