Results 41 to 50 of about 24,157 (174)

Biochemical testing and pathology reveal rare cause of pediatric acute liver failure: Hyperornithinemia‐hyperammonemia‐homocitrullinuria syndrome

JPGN Reports, EarlyView.
Abstract Hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome is a rare metabolic condition that can cause lethargy, ataxia, tachypnea, nausea, vomiting, seizures, coma, and acute liver failure. We present a 26‐month‐old female with acute liver failure who was diagnosed with HHH 1 week after admission. Histology revealed an acute hepatitic
Tierra L. Mosher, Kathryn S. Czepiel, Matthew B. Neu, Andrea Carolina Cortes Fernandez, L. Walden Browne, Annie D. Niehaus, Roberto Gugig   +6 more
wiley   +1 more source

Evaluation of salivary ceruloplasmin for the diagnosis of Wilson’s disease

Scientific Reports
The serum ceruloplasmin assay is the most commonly used test for diagnosing Wilson’s disease (WD). Despite the utility of non-invasive tests for diagnosing WD, no such tests have been developed.
Nian Zhang, Limin Wu, Pengyu Jiang, Zhihui Ji, Miaozhu Yin, Huan Zhou, Lei He, Zehua Xia, Fengying Wang, Xin Xiao, Hui Han   +10 more
doaj   +1 more source

Correlation of Serum zinc with TSH in hyperthyroidism

Asian Journal of Medical Sciences, 2015
Aims and Objectives: Trace elements may have a role in progression of hyperthyroidism. We planned to estimate the serum zinc, copper and ceruloplasmin in hyperthyroids. Materials and Methods: 41 hyperthyroid patients and 32 control subjects were taken
Satwika Sinha
doaj   +1 more source

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

JPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi, Rachel Schenker, Nick Shillingford, George Yanni   +3 more
wiley   +1 more source

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source

Assessment of Serum Ceruloplasmin Levels in Gingivitis, Chronic and Aggressive Periodontitis Patients- A Clinico-Biochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Pro-inflammatory mediators are mainly responsible for periodontal tissue breakdown in periodontitis. Ceruloplasmin is one such biomarker, the levels of which seems to be elevated in presence of inflammation.
Shrinidhi Maji Shankar, KC Chethana, G Kavyashree, BG Soumya, Kala Bushan, TP Shiva Kumar   +5 more
doaj   +1 more source

More than just anemia: Uncovering celiac disease beneath the surface: A case report

JPGN Reports, EarlyView.
Abstract Celiac disease (CD) is an immune‐mediated disorder triggered by gluten in genetically susceptible individuals. Although iron deficiency anemia is a common presentation, other micronutrient deficiencies may occur. We describe a 3.5‐year‐old female whose initial presentation of CD was severe, asymptomatic normocytic anemia secondary to copper ...
Evan Greenhall, Bri Best, David F. Carpenteri, Paula Prieto‐Tizzard   +3 more
wiley   +1 more source

Disseminated histoplasmosis mimicking autoimmune hepatitis as a trigger of secondary hemophagocytic lymphohistiocytosis in a pediatric patient

JPGN Reports, EarlyView.
Abstract Patients presenting with hemophagocytic lymphohistiocytosis (HLH) are often critically ill, and rapid identification of both HLH and underlying triggers in secondary HLH is essential for successful treatment. We present a case of secondary HLH activated by disseminated histoplasmosis (DH) that mimicked autoimmune hepatitis (AIH) on liver ...
Thomas Ratchford, Talal Al Hendawi, Eumenia Castro, Pelin Cengiz, James Conway, Shelly Cook, Leanne Mansfield, Nicholas Pytel, Christine M. Seroogy, Katelyn Watkin, Jo Wilson, Jonathan Wong, Therese Woodring, Katryn N. Furuya   +13 more
wiley   +1 more source

Alteration of ceruloplasmin in patients with malaria: a systematic review and meta-analysis of observational studies

Malaria Journal
Background The evidences of oxidative stress-related Plasmodium infection may alter the ceruloplasmin levels were inconsistent. This systematic review and meta-analysis aimed to collate and synthesize literatures on malaria and ceruloplasmin ...
Kwuntida Uthaisar Kotepui, Aongart Mahittikorn, Polrat Wilairatana, Frederick Ramirez Masangkay, Manas Kotepui   +4 more
doaj   +1 more source

Sulfasalazine Enhances Copper Toxicity in Danio rerio Larvae: Divergent Protective Roles of Deferoxamine and Ferrostatin‐1

Environmental Toxicology, EarlyView.
ABSTRACT Copper is an environmental contaminant capable of disrupting redox homeostasis and impairing antioxidant defenses in aquatic organisms, thereby increasing susceptibility to oxidative stress. The cystine/glutamate antiporter (system xc−) plays a central role in maintaining intracellular glutathione (GSH) levels, a major antioxidant defense ...
Maria Vitória Takemura Mariano, Pedro Henrique Vicenzi, Vitor Oliveira de Rosso, Mauro Eugênio Medina Nunes, Layla da Silva Braga, Analía Del Valle Garnero, Ricardo José Gunski, Marcelo Farina, Thaís Posser, Jeferson Luis Franco   +9 more
wiley   +1 more source