Results 41 to 50 of about 32,896 (166)

Correlation of Serum zinc with TSH in hyperthyroidism

Asian Journal of Medical Sciences, 2015
Aims and Objectives: Trace elements may have a role in progression of hyperthyroidism. We planned to estimate the serum zinc, copper and ceruloplasmin in hyperthyroids. Materials and Methods: 41 hyperthyroid patients and 32 control subjects were taken
Satwika Sinha
doaj   +1 more source

Assessment of Serum Ceruloplasmin Levels in Gingivitis, Chronic and Aggressive Periodontitis Patients- A Clinico-Biochemical Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Pro-inflammatory mediators are mainly responsible for periodontal tissue breakdown in periodontitis. Ceruloplasmin is one such biomarker, the levels of which seems to be elevated in presence of inflammation.
Shrinidhi Maji Shankar, KC Chethana, G Kavyashree, BG Soumya, Kala Bushan, TP Shiva Kumar   +5 more
doaj   +1 more source

Ceruloplasmin and iron in Alzheimer's disease and Parkinson's disease: a synopsis of recent studies. [PDF]

, 2012
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field.Ceruloplasmin (Cp) concentration and oxidative activity in serum are lowered in Parkinson's disease (PD).
Jóhannesson, Torkell, Kristinsson, Jakob, Snaedal, Jón, Tórsdóttir, Gudlaug   +3 more
core   +1 more source

The Renal Activity Index for Lupus Identifies Active Renal Disease and Treatment Response in Adult Patients With Systemic Lupus Erythematosus and Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective We evaluated the ability of the Renal Activity Index for Lupus (RAIL) to discriminate active lupus nephritis (LN) in adult patients with active systemic lupus erythematosus (SLE) and differentiate LN treatment response. Methods Urine samples from adults with biopsy‐proven active class III and IV LN from TULIP‐LN (active LN group ...
Hermine I. Brunner, Ellen M. Cody, Prasad Devarajan, Bin Huang, Chen Chen, Dominic Sinibaldi, Madhu Ramaswamy, Jacob Knagenhjelm, Frederick Jones, Philip Z. Brohawn, Raj Tummala, Catharina Lindholm, Wendy I. White   +12 more
wiley   +1 more source

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu, Taiheng Ma, Qi Liu, He Zhu, Zheng Fang, Jiahong Ma, Ting Yu, Yan Wang, Jiahua Zhou, Xiaoyan Liu, Yaqian Li, Zhimou Guo, Xinmiao Liang, Mingming Dong, Deguang Sun, Mingliang Ye   +15 more
wiley   +1 more source

Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response [PDF]

, 2014
Exposure of lung to hypoxia has been previously reported to be associated with significant alterations in the protein content of bronchoalveolar lavage (BAL) and lung tissue.
Floros, Joanna, López Barneo, José, Olmeda, Bárbara, Pascual Bravo, Alberto, Phelps, David S., Pérez Gil, Jesús, Silveyra, Patricia, Umstead, Todd M.   +7 more
core   +1 more source

Evaluation of salivary ceruloplasmin for the diagnosis of Wilson’s disease

Scientific Reports
The serum ceruloplasmin assay is the most commonly used test for diagnosing Wilson’s disease (WD). Despite the utility of non-invasive tests for diagnosing WD, no such tests have been developed.
Nian Zhang, Limin Wu, Pengyu Jiang, Zhihui Ji, Miaozhu Yin, Huan Zhou, Lei He, Zehua Xia, Fengying Wang, Xin Xiao, Hui Han   +10 more
doaj   +1 more source

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]

, 2009
Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine, Gabius, Hans-Joachim, Kojima, Shuji, Kozar, Tibor, Unverzagt, Carlo   +4 more
core   +1 more source

Relative Exchangeable Copper Confirms Wilson Disease and Supports Reclassification of the ATP7B p.Met665Ile Variant With Conflicting Pathogenicity Evidence

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by ATP7B mutations. Diagnosis is usually straightforward in symptomatic patients, but can be challenging in children and adolescents with mild liver disease, borderline urinary copper excretion, or inconclusive genetic findings.
Emanuele Nicastro, Caterina Zuccoli, Roberto Marozzi, Antonino Barletta, Lisa Licini, Paola Tebaldi, Valeria Casotti, Mariangela Stinco, Lidia Pezzani, Maria Iascone, Lorenzo D'Antiga   +10 more
wiley   +1 more source

Truncating mutations in the Wilson disease gene ATP7B are associated with very low serum ceruloplasmin oxidase activity and an early onset of Wilson disease [PDF]

, 2010
Background Mutations in the gene ATP7B cause Wilson disease, a copper storage disorder with a high phenotypic and genetic heterogeneity. We aimed to evaluate whether 'severe' protein-truncating ATP7B mutations (SMs) are associated with low serum ...
Uta Merle, Karl Heinz Weiss, Christoph Eisenbach, Sabine Tuma, Peter Ferenci, Wolfgang Stremmel   +5 more
core   +1 more source