Results 51 to 60 of about 32,896 (166)

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

Angewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Wang, Hegne Pupart, Xun Sun, Jan Gui‐Hyon Dreiser, Peep Palumaa, Qinghua Liao, Matthias Krack, Jinghui Luo   +9 more
wiley   +1 more source

Ceruloplasmin expression by human peripheral blood lymphocytes: a new link between immunity and iron metabolism [PDF]

, 2008
Ceruloplasmin (CP) is a multicopper oxidase involved in the acute phase reaction to stress. Although the physiological role of CP is uncertain, its role in iron (Fe) homeostasis and protection against free radical-initiated cell injury has been widely ...
Akbar, Akbar, Aldred, Babu, Babu, Bala, Bomford, Bourbon, Cairo, Camacho, Cardoso, Cousins, Cruz, Daimon, De Sousa, de Sousa, de Sousa, Deborah Penque, Del Rey, Dina Pereira, Dorner, Eleonora Paixão, Feder, Fleming, Fortna, Fox, Frieden, Gerhard, Gitlin, Giustiniani, Goldstein, Graf, Hall, Harris, Hellman, Hellman, Itoh, Jaeger, João Banha, Klebanoff, Klomp, Knekt, Laine, Liliana Marques, Luciana Costa, Maria de Fátima Martins, Mazumder, Mittal, Moak, Osaki, Osaki, Pan, Patel, Patel, Phillips, Platonova, Porto, Pousset, Ramadori, Rita Oliveira, Rui Malhó, Santos, Senra Varela, Soltys, Stremmel, Van Eden, Van Snick, Weinberg, Weiss, Winnock, Yang   +70 more
core   +1 more source

Protein‐Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation

Angewandte Chemie International Edition, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann, Chang Liu, Xue Wang, Hegne Pupart, Xun Sun, Jan Gui‐Hyon Dreiser, Peep Palumaa, Qinghua Liao, Matthias Krack, Jinghui Luo   +9 more
wiley   +1 more source

Study of serum copper and ceruloplasmin levels in Egyptian autistic children

Egyptian Journal of Medical Human Genetics, 2018
Background: Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Objective: To assess serum copper and ceruloplasmin levels in Egyptian autistic children patients.
Farida El-Baz, Mohamed E. Mowafy, Ahmed Lotfy   +2 more
doaj   +1 more source

Quercetin Affects Erythropoiesis and Heart Mitochondrial Function in Mice [PDF]

, 2015
Copyright © 2015 Lina M. Ruiz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Barreto, Marlen, Elorza, Alvaro A, Jensen, Erik, Quintanilla, Rodrigo A, Ruiz Hincapie, Paula, Ruiz, Lina M, Salazar, Celia, Tiznado, William   +7 more
core   +5 more sources

Use of Restricted Nursing and a Bovine Appeasing Substance on the Welfare, Growth Performance, and Response to Vaccination of Beef Calves at Weaning

Animal Research and One Health, EarlyView.
The effects of restricted nursing (RN) and the administration of a bovine appeasing substance (BAS) on days −8 and 0 in relation to weaning were evaluated. Both strategies were effective in improving the growth performance of beef calves. Regarding welfare, BAS ‐especially on day 0‐ was more effective than RN.
Denise E. Mussalafo, Marcelo Vedovatto, Aylpy R. D. Santos, Dalton M. Oliveira, Fabiana A. M. Sterza, Mariana Santos, Helena B. C. R. Batista, Jaíne G. Garcia, Andréa R. D. L. Souza   +8 more
wiley   +1 more source

Alteration of ceruloplasmin in patients with malaria: a systematic review and meta-analysis of observational studies

Malaria Journal
Background The evidences of oxidative stress-related Plasmodium infection may alter the ceruloplasmin levels were inconsistent. This systematic review and meta-analysis aimed to collate and synthesize literatures on malaria and ceruloplasmin ...
Kwuntida Uthaisar Kotepui, Aongart Mahittikorn, Polrat Wilairatana, Frederick Ramirez Masangkay, Manas Kotepui   +4 more
doaj   +1 more source

The effect of amino acid deprivation on the transfer of iron through Caco-2 cell monolayers [PDF]

, 2017
Funding Source Rural and Environmental Scientific and Analytical Services, the Scottish Government Acknowledgments We thank Dr Helen Hayes for her technical support during this project.
Cottin, Sarah, McArdle, Harry J., Roussel, Guenievre, Stevens, Valerie   +3 more
core   +3 more sources

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

Exploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng, Tao Zhu, Yueyang Wang, Sitong Zhang, Hong Deng, Guilan Quan, Tingting Peng, Chuanbin Wu, Huiqiang Cai, Chao Lu, Xiaopeng Cai   +10 more
wiley   +1 more source