Results 51 to 60 of about 52,504 (265)

Spinal canal stenosis at the level of Atlas

Journal of Craniovertebral Junction and Spine, 2011
We report here a rare case of high cervical stenosis at the level of atlas who presented with progressively deteriorating quadriparesis and respiratory distress.
Suchanda Bhattacharjee, Vijayasaradhi Mudumba, Purohit K Aniruddh   +2 more
doaj   +1 more source

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]

, 2015
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa, Kurzrock, Razelle, Schwaederle, Maria   +2 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The relationship between vertical malocclusions and ossification changes in the cranial base and upper cervical spine

Scientific Reports
The growth and development of the maxillofacial complex share a common embryological origin with the cranial base and upper cervical spine; therefore, anomalies in these regions may be linked to variations in the skeletal pattern.
Roberta Lekavičiūtė, Diana Šopagienė, Giedrė Trakinienė, Kristina Lopatienė   +3 more
doaj   +1 more source

Two judicial postmortems that went awry 1870 & 1908 [PDF]

, 1996
The first instance of an exhumation of a cadaver for a judicial post-mortem took place in 1870 in connection with a murder case. Knowledge, on the part of the pathologist, of the scene of the crime and of the events leading to the murder are important as
Cassar, Paul
core  

Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]

, 2016
The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita, Deng, Wenbing, Gong, Wenrong, Qin, Xin, Yu, Hongjun, Zhang, Min   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Bony bridges and selected variations of the first cervical vertebra (Atlas): A brief encyclopedic overview with comments on clinical and neurological implications

Translational Research in Anatomy
Background: The first cervical vertebra, the atlas (C1), is a unique and complex structure responsible for supporting the skull and facilitating head movement. Due to its intimate anatomical relationship with the vertebral artery and cervical nerves, any
Robert Haładaj, Roksana Haładaj, Nikola Haładaj, Ivan Varga   +3 more
doaj   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Spinabifida of atlas

National Journal of Clinical Anatomy, 2012
During the routine osteology demonstration for the first year MBBS students, the authors came across the presence of incomplete posterior arch in one of the atlas.
K Padmalatha, B S Prakash, N Balachandra, Y Mamatha   +3 more
doaj   +1 more source