Results 1 to 10 of about 2,385 (96)
Spatial and Temporal Patterns of Prion Gene Variation Are Consistent With a Response to Chronic Wasting Disease‐Induced Selection in Wild White‐Tailed Deer [PDF]
Ecology and EvolutionChronic wasting disease (CWD) poses a threat to cervids and is increasingly prevalent throughout North America. Prion protein gene (PRNP) variation may confer some degree of genetic resilience, creating an impetus to examine changes in allelic variation ...
Christine M. Bubac +6 more
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A review of chronic wasting disease (CWD) spread, surveillance, and control in the United States captive cervid industry [PDF]
PrionChronic wasting disease (CWD) is a fatal prion disease of the family Cervidae that circulates in both wild and captive cervid populations. This disease threatens the health and economic viability of the captive cervid industry, which raises cervids in ...
Jameson Mori +3 more
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Differences between the white-tailed and mule deer chronic wasting disease agents after passage through sheep [PDF]
Frontiers in Veterinary ScienceBackgroundChronic wasting disease (CWD) is a fatal prion disease that affects the cervid species, including white-tailed deer (WTD) (Odocoileus virginianus) and mule deer (MD) (Odocoileus hemionus). Interspecies transmission of CWD is highly variable and
Alexis J. Frese +9 more
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Effect of primary structural variation on cervid prion protein in flexibility, stability, and spontaneous misfolding propensity [PDF]
Neurobiology of DiseaseProtein misfolding is central to numerous neurodegenerative disorders, collectively known as proteinopathies, which include Alzheimer's disease, Parkinson's disease, and prion diseases, among others.
Carlos M. Díaz-Domínguez +13 more
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Chronic Wasting Disease Transmission Risk Assessment for Farmed Cervids in Minnesota and Wisconsin
Viruses, 2021 CWD (chronic wasting disease) has emerged as one of the most important diseases of cervids and continues to adversely affect farmed and wild cervid populations, despite control and preventive measures.
James M. Kincheloe +3 more
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Emerging Microbes and Infections, 2022 SARS-CoV-2 was first reported circulating in human populations in December 2019 and has since become a global pandemic. Recent history involving SARS-like coronavirus outbreaks have demonstrated the significant role of intermediate hosts in viral ...
Konner Cool +19 more
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Genetics and Molecular Biology, 2022 Blastocerus dichotomus is the largest deer in South America. We have used 25 microsatellite markers detected and genotyped by Next Generation Sequencing to estimate the genetic variability of B.
Laura Irene Wolfenson +4 more
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Spatio-temporal analyses reveal infectious disease-driven selection in a free-ranging ungulate
Royal Society Open Science, 2021 Infectious diseases play an important role in wildlife population dynamics by altering individual fitness, but detecting disease-driven natural selection in free-ranging populations is difficult due to complex disease–host relationships.
Melanie E. F. LaCava +5 more
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Frontiers in Immunology, 2023 Prion diseases are a novel class of infectious disease based in the misfolding of the cellular prion protein (PrPC) into a pathological, self-propagating isoform (PrPSc).
Scott Napper +2 more
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Animals, 2023 Forty-four fallow deer bucks (10 months old; 22.9 ± 2.4 kg) were utilized to investigate the effects of immunocastration and amino acid supplementation on testes development. Immunocastrated bucks were administered Improvac® at weeks 1, 8, and 20 of this
Thoniso Chitambala +6 more
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