Results 41 to 50 of about 77,111 (304)

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

P16 expression in squamous cell carcinomas of cervix and bladder

, 2010
p16 is a widely used immunohistochemical marker in gynecologic pathology. Strong and diffuse cytoplasmic and nuclear expression of p16 in squamous cell carcinomas (SCC) of the female genital tract is strongly associated with high-risk human papilloma ...
Chapman-Fredricks, Jennifer, Ganjei-Azar, Parvin, Gomez-Fernandez, Carmen, Jorda, Merce, Manoharan, Murigesan, Cioffi-Lavina, Maureen   +5 more
core   +1 more source

Female Genital Tract Involvement in Acute Lymphoblastic Leukemia: A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Female Genital Tract (FGT) involvement with hematologic neoplasms is uncommon and the hematologic malignancies which involve the female genital organs are usually non-Hodgkin’s lymphoma.
Vikram Narang, Amit Dhiman, Bhavna Garg, Neena Sood   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Primary analysis of malignant neoplasm trends and demographics in hospitalized patients in Kashi prefecture from 2016 to 2023

BMC Cancer
Objective To analyze the ranking, composition, trend changes, and distribution by gender and ethnicity of malignant neoplasms in hospitalized patients in the Kashi prefecture from 2016 to 2023. This analysis aims to provide a reference for the prevention
Nueraili Kade, Wusiman Yakufu, Cheng Zhang, Lin Wang, Qingqing Qian, Xiaochuan Liu, Long Jia, Chunfeng Wu, Weihua Chen, Tianxiang Chen   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

SARCOMATOID DIFFUSE LARGE B-CELL LYMPHOMA: A RARE MORPHOLOGICAL VARIANT WITH MULTI-VISCERAL INVOLVEMENT

Hematology, Transfusion and Cell Therapy, 2021
Introduction: Diffuse Large B-Cell Lymphoma (DLBCL) is the most frequent subtype of non-Hodgkin's lymphoma (NHL), accounting for 50% of all NHL cases seen at HC-FMUSP. Up to 40-50% of DLBCL cases have extranodal involvement. However, female genital tract
PPF Machado, GGM Lima, LF Castelo, V Rocha, LAPC Lage, J Pereira   +5 more
doaj   +1 more source

Synchronous primary malignant neoplasms of the cervix and endometrium

Molecular and Clinical Oncology, 2017
Synchronous multiple malignant neoplasms of the female genital tract are rare, particularly in the uterus. We herein present the case of a patient with synchronous cervical squamous epithelial carcinoma and endometrial adenocarcinoma, and discuss the diagnosis, treatment and prognosis. The patient underwent a cervical biopsy and fractional curettage of
Lv, Shulan, Xue, Xue, Sui, Yanxia, Du, Juang, Zou, Junkai, Sun, Chao, Liu, Dong, Song, Qing, Li, Qiling   +8 more
openaire   +3 more sources

Neuroendocrine Neoplasms of the Gynecologic Tract

, 2022
Gynecological tract neuroendocrine neoplasms (NEN) are rare, aggressive tumors from endocrine cells derived from the neuroectoderm, neural crest, and endoderm.
Sai Swarupa Vulasala, Rebecca Waters, Priya Bhosale, Dheeraj R. Gopireddy, Chandana Lall, Mayur Virarkar, Sindhu Kumar, Ajaykumar C. Morani   +7 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source