Results 191 to 200 of about 395,530 (242)

From Concept to Clinic: Pre‐Clinical Testing and Regulatory Considerations in Spine Implant Development

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Spine implant development follows a regulated, iterative pathway from clinical need and design through material selection, prototyping, preclinical validation, and regulatory approval to post‐market surveillance. Biomechanical evaluation and risk‐based frameworks integrate across all stages, ensuring safe, effective translation from concept to clinical
Amit Benady   +5 more
wiley   +1 more source

The Impact of Substance Abuse Problems and Serious Mental Illness/Serious Emotional Distress on Post‐Discharge Residential Status Among Clients With Behavioral and Cognitive Disorders: Evidence From SAMHSA MH‐CLD Data

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
SAP was linked to 40% increased odds of non‐private discharge (aOR = 1.40, 95% CI: 1.18–165), and SMISED had about two‐fold increased odds (aOR = 2.10, 95% CI: 1.44–3.05) compared to discharge in private residence. For individuals with SAP, unemployed Hispanic/Latino clients showed the highest odds of non‐private discharge compared to employed clients (
Eden Moges   +3 more
wiley   +1 more source

Clinical outcomes of a new modified tubeless cutaneous ureterostomy following radical cystectomy. [PDF]

open access: yesTransl Androl Urol
Huang H   +9 more
europepmc   +1 more source

Emerging Applications of Additive Manufacturing in Aquaculture Systems: A Comprehensive Review

open access: yesReviews in Aquaculture, Volume 18, Issue 3, June 2026.
Additive manufacturing (3D printing) is transforming aquaculture through smart monitoring, customized components, feeding systems, water quality control, and sustainable production. ABSTRACT This review provides a comprehensive analysis of the existing literature on additive manufacturing, commonly known as three‐dimensional (3D) printing, in ...
Subha M. Roy, Hyunsoo Choi, Taeho Kim
wiley   +1 more source

Coronary Microvascular Dysfunction in Cardiomyopathies: Insights on Clinical and Prognostic Roles. [PDF]

open access: yesRev Cardiovasc Med
Giacobbe F   +20 more
europepmc   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1205-1215, May 2026.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco   +17 more
wiley   +1 more source

Symptom phenotypes and coronary microvascular function in non-obstructive coronary artery disease: Insights beyond epicardial ischemia. [PDF]

open access: yesAm Heart J Plus
Matsumoto K   +16 more
europepmc   +1 more source

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