Results 131 to 140 of about 71,270 (242)

The Spectrum and Frequency of Cystic Fibrosis Mutations in Albanian Patients

Balkan Journal of Medical Genetics
Cystic fibrosis (CF) is a genetic disease characterized by a wide spectrum of severity, resulting from the inheritance of a mutant allele of the gene for cystic fibrosis transmembrane conductance regulator (CFTR).
Kasmi I, Kasmi G, Basholli B, Sefa HS, Vevecka E   +4 more
doaj   +1 more source

The Role of Nontuberculous Mycobacteria in Patients With Cystic Fibrosis Advanced Lung Disease

Transplant Infectious Disease, EarlyView.
Among 270 cystic fibrosis patients, 20.7% were NTM‐positive and had a lower pre‐transplant risk of death or lung transplantation but higher post‐transplant mortality, with no difference in CLAD incidence. These results suggest NTM infection should not be an absolute contraindication to lung transplantation, though careful individual risk assessment is ...
Shirin Barcikowski, Ribal Bou Mjahed, Oriol Manuel, Macé M. Schuurmans, Adrian Alonso, Zisis Balmpouzis, Jesica Mazza‐Stalder, Angela Koutsokera, Nicolas J. Mueller   +8 more
wiley   +1 more source

‘The Hero's journey’: Narratives on the transition to motherhood with cystic fibrosis

British Journal of Health Psychology, Volume 31, Issue 2, May 2026.
Abstract Objectives This study aimed to explore the impact of cystic fibrosis (CF) on the transition to motherhood using a strength‐based narrative approach. It sought to elevate the voices of women with CF and examine how they navigate pregnancy and early motherhood in the context of chronic illness. Design A qualitative narrative study was conducted,
Alena J. Haines, Lynette Mackenzie, Anne Honey, Peter Middleton   +3 more
wiley   +1 more source

Epigenetic Alterations Beyond CpG Islands in Periodontitis: In Silico Study of DNA Methylation Data

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives To classify differentially methylated CpG sites in periodontitis based on methylation shift direction and location relative to CpG islands. Material and Methods We integrated DNA methylation data from 65 gingival samples (31 periodontitis, 34 healthy) from three GEO datasets.
Koki Yoshida, Gowri Sivaramakrishnan, Farah Asa'ad   +2 more
wiley   +1 more source

3D Automated Segmentation of Bronchial Abnormalities on Ultrashort Echo Time MRI: A Quantitative MR Outcome in Cystic Fibrosis

Journal of Magnetic Resonance Imaging, Volume 63, Issue 4, Page 1190-1200, April 2026.
ABSTRACT Background Cystic fibrosis (CF) monitoring relies on computed tomography (CT), but ultra‐short echo time MRI (UTE‐MRI) offers a radiation‐free alternative. However, its clinical adoption is hindered by the laborious and subjective manual analysis, which prevents standardized quantification of bronchial abnormalities.
Amel Imene Hadj Bouzid, Ilyes Benlala, Baudouin Denis de Senneville, Fabien Baldacci, Julie Macey, Wadie Benhassen, Pan Su, Stephanie Bui, Maeva Zysman, Aurelien Bustin, Patrick Berger, Gael Dournes   +11 more
wiley   +1 more source

Phenotype, Management, and Outcomes in Paediatric Acute Pancreatitis: A Real‐Life Cross‐Sectional Study

Acta Paediatrica, Volume 115, Issue 4, Page 951-958, April 2026.
ABSTRACT Aim Limited Canadian data on paediatric acute pancreatitis exist. A meta‐analysis of 48 studies reported equal prevalence of acute pancreatitis among various aetiologies, with rates of severe acute pancreatitis at 13.7% in North America.
Catherine Korman, Doha Elhaoua, Sarah Blain, Thomas Li, Mariam Mohamed, Alessandro David, Colette Deslandres, Ugur Halac, Martha Dirks, Kelly Grzywacz, Michel Lallier, Fernando Alvarez, Prévost Jantchou   +12 more
wiley   +1 more source

Making Molecular Diagnostics Faster

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 272-280, April 2026.
ABSTRACT Background Over the past 40 years, molecular diagnostic methods have evolved from multi‐step, time‐consuming protocols towards either rapid targeted tests or expansive, massively parallel testing. Aims Here we consider the speed limits of targeted molecular diagnostics, considering the three sequential required steps: nucleic acid preparation,
Carl T. Wittwer, Luming Zhou, Felix Ye, Adam Millington, Adrian de Cola, Noriko Kusukawa   +5 more
wiley   +1 more source

Search for proteins with similarity to the CFTR R domain using an optimized RDBMS solution, mBioSQL

Open Life Sciences, 2006
Hegedűs Tamás, Riordan John
doaj   +1 more source

Antisense oligonucleotide targeting the E3 ligase RFFL potentiates CFTR modulator efficacy in CF primary bronchial epithelial cells

Molecular Therapy: Nucleic Acids
Cystic fibrosis (CF) is most commonly caused by the ΔF508 mutation in the CFTR gene, leading to misfolding and degradation of the CFTR protein. Although CFTR modulators such as elexacaftor/tezacaftor/ivacaftor (ETI) provide clinical benefit, their ...
Daichi Hinata, Yukari Kai, Ryosuke Fukuda, Yuka Kamada, Yuuya Kasahara, Kiyomi Sasaki, Tokuyuki Yoshida, Satoshi Obika, Takao Inoue, Tsukasa Okiyoneda   +9 more
doaj   +1 more source

H+ és HCO3- transzporterek szabályozása humán pancreas ductus sejtekben = Regulation of H+ and HCO3-Transporters in Human Pancreatic Duct Cells [PDF]

, 2009
A pancreas nedvben található HCO3- ionok kiválasztásáért a pancreas ductus sejtek felelősek. Jelen pályázatban célul tűztük ki, hogy molekuláris biológiai, transzdukciós és mikrofluorescens technikák felhasználásával megértsük a HCO3- szekréció ...
Rakonczay, Zoltán
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